DFNB1 non-syndromic hearing impairment: Diversity of mutations and associated phenotypes

FJ Del Castillo, I Del Castillo - Frontiers in molecular neuroscience, 2017 - frontiersin.org
The inner ear is a very complex sensory organ whose development and function depend on
finely balanced interactions among diverse cell types. The many different kinds of inner ear …

Prognostic indicators in paediatric cochlear implant surgery: a systematic literature review

J Black, L Hickson, B Black, C Perry - Cochlear implants …, 2011 - Taylor & Francis
Background Paediatric cochlear implantation (PCI) requires complex case evaluation and
counselling, surgical intervention, and habilitation. Outcomes vary and many cases have …

Prediction of cochlear implant performance by genetic mutation: the spiral ganglion hypothesis

RW Eppsteiner, AE Shearer, MS Hildebrand… - Hearing research, 2012 - Elsevier
BACKGROUND: Up to 7% of patients with severe-to-profound deafness do not benefit from
cochlear implantation. Given the high surgical implantation and clinical management cost of …

A comprehensive study on the etiology of patients receiving cochlear implantation with special emphasis on genetic epidemiology

M Miyagawa, SY Nishio, SI Usami - Otology & Neurotology, 2016 - journals.lww.com
Objective: Cochlear implantation is the most important treatment currently available for
profound sensorineural hearing loss. The aim of this study was to investigate the etiology of …

Evolution of communication abilities after cochlear implantation in prelingually deaf children

JM Gérard, N Deggouj, C Hupin, AL Buisson… - International journal of …, 2010 - Elsevier
OBJECTIVE: This study tries to evaluate different factors on communication ability outcomes
in cochlear implanted children. METHODS: Communication abilities are studied using the …

Predictive Value of GJB2 Mutation Status for Hearing Outcomes of Pediatric Cochlear Implantation

Y Abdurehim, A Lehmann… - … –Head and Neck …, 2017 - journals.sagepub.com
Objective To systematically review and quantify current evidence regarding the association
of GJB2 mutation status with outcomes of pediatric cochlear implantation. Data Sources …

Auditory skills, language development, and adaptive behavior of children with cochlear implants and additional disabilities

J Beer, MS Harris, WG Kronenberger… - … journal of audiology, 2012 - Taylor & Francis
Objective: The objective of this study was to evaluate the development of functional auditory
skills, language, and adaptive behavior in deaf children with cochlear implants (CI) who also …

The effect of GJB2 and SLC26A4 gene mutations on rehabilitative outcomes in pediatric cochlear implant patients

Y Yan, Y Li, T Yang, Q Huang, H Wu - European Archives of Oto-Rhino …, 2013 - Springer
To analyze the treatment outcomes in pediatric cochlear implant patients with mutations in
GJB2 or SLC26A4 and to determine these mutations' impact on rehabilitative outcomes. The …

Genotype-phenotype correlation for predicting cochlear implant outcome: Current challenges and opportunities

AA Eshraghi, SP Polineni, C Davies, D Shahal… - Frontiers in …, 2020 - frontiersin.org
The use and utility of cochlear implantation has rapidly increased in recent years as
technological advances in the field have expanded both the efficacy and eligible patient …

Predominance of genetic diagnosis and imaging results as predictors in determining the speech perception performance outcome after cochlear implantation in …

CC Wu, YC Lee, PJ Chen, CJ Hsu - Archives of pediatrics & …, 2008 - jamanetwork.com
Objective To investigate the roles of genetic diagnosis and imaging studies, as well as other
prognostic factors, in predicting outcomes in children with cochlear implant. Design …