The rapid development of artificial intelligence (AI) technologies in the context of the vast
amount of collectable data obtained from high-throughput sequencing has led to an …

Single-cell omics aim at charting the different types and properties of all cells in the human
body in health and disease. Over the past years, myriads of cellular phenotypes have been …

Stimulator of interferon genes (STING) is an intracellular sensor of cyclic di-nucleotides
involved in the innate immune response against pathogen-or self-derived DNA. STING …

Extracellular vesicles (EVs) play an important role in intercellular communication as carriers
of signalling molecules such as bioactive miRNAs, proteins and lipids. EVs are key players …

Huntington's disease (HD) is a dominant neurological disorder caused by an expanded HTT
exon 1 CAG repeat that lengthens huntingtin's polyglutamine tract. Lowering mutant …

Cancers feature substantial intratumoral heterogeneity of genetic and phenotypically distinct
lineages. Although interactions between coexisting lineages are emerging as a potential …

Background & Aims Drug-induced liver injury (DILI), both intrinsic and idiosyncratic, causes
frequent morbidity, mortality, clinical trial failures and post-approval withdrawal. This …

ABSTRACT 2019 coronavirus disease (COVID-19) is a disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to respiratory illness, COVID …

Artificial intelligence (AI) can acquire characteristics that are not yet known to humans
through extensive learning, enabling to handle large amounts of pathology image data …

Mammalian blastocyst formation involves the specification of the trophectoderm followed by
the differentiation of the inner cell mass into embryonic epiblast and extra-embryonic …