Adipose cells store lipids in the cytoplasm and signal systemically through secretion of
adipokines and other molecules that regulate body energy metabolism. Differentiation of fat …

Small heterodimer partner-interacting leucine zipper (SMILE) is a member of the CREB/ATF
family of basic leucine zipper (bZIP) transcription factors. SMILE has two isoforms, a small …

Background Although anti–tumor necrosis factor (TNF) agents are effective in patients with
inflammatory bowel disease (IBD), many patients either do not respond to anti-TNF …

Retinol is an essential nutrient in animals. Its metabolites, specifically retinoic acid (RA), are
crucial for cell differentiation, including adipogenesis. Retinol binding protein 7 (Rbp7) is …

Objective Osteoarthritis (OA) is a degenerative joint disease caused by the breakdown of
joint cartilage and adjacent bone. Joint injury, being overweight, differences in leg length …

Small heterodimer partner interacting leucine zipper protein (SMILE) is an orphan nuclear
receptor and a member of the bZIP family of proteins. We investigated the mechanism by …

The liver is one of the first organs affected by accumulated ectopic lipids. Increased de novo
lipogenesis and excessive triglyceride accumulation in the liver are hallmarks of …

Vitamin A, referred to as retinol, is an essential nutrient that affects the cell growth and
differentiation including adipogenesis. Although previous studies using supraphysiological …

ABSTRACT CREBZF (cAMP-response element binding protein zhangfei) is a member of
ATF/CREB family, and which regulates various cellular functions by suppressing major …

Objective: The aim of this study is to investigate the antihyperglycemic activity of
tinocrisposide by stimulating 3T3-L1 adipocyte cell differentiation. Tinocrisposide is a …