Eosinophilia

A Kovalszki, PF Weller - Primary care, 2016 - pmc.ncbi.nlm.nih.gov
Eosinophilia represents an increased number of eosinophils in the tissues and/or blood.
Although enumeration of tissue eosinophil numbers would require examination of biopsied …

Drug-induced severe cutaneous adverse reactions: insights into clinical presentation, immunopathogenesis, diagnostic methods, treatment, and pharmacogenomics

T Tempark, S John, P Rerknimitr… - Frontiers in …, 2022 - frontiersin.org
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased
duration of hospital stays and the associated cost burden are common issues, and in the …

Worldwide prevalence of antibiotic-associated Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis

EY Lee, C Knox, EJ Phillips - JAMA dermatology, 2023 - jamanetwork.com
Importance Antibiotics are an important risk for Stevens-Johnson syndrome and toxic
epidermal necrolysis (SJS/TEN), which are the most severe types of drug hypersensitivity …

Allopurinol use and risk of fatal hypersensitivity reactions: a nationwide population-based study in Taiwan

CY Yang, CH Chen, ST Deng, CS Huang… - JAMA internal …, 2015 - jamanetwork.com
Importance Allopurinol, a first-line drug used for treating gout, is increasingly prescribed
worldwide to patients with asymptomatic hyperuricemia and comorbid renal or …

Incidence of Stevens-Johnson syndrome and toxic epidermal necrolysis: a nationwide population-based study using national health insurance database in Korea

MS Yang, JY Lee, J Kim, GW Kim, BK Kim, JY Kim… - PloS one, 2016 - journals.plos.org
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-
threatening diseases; however, it is hard to estimate their incidence due to the rarity of these …

Cutaneous adverse drug reactions in Indian population: A systematic review

TK Patel, SH Thakkar, DC Sharma - Indian dermatology online …, 2014 - journals.lww.com
Background: Epidemiological data is limited for cutaneous adverse drug reactions (CADRs)
in India. Most of the Indian studies have small sample size and are of limited duration. Aims …

Ethno‐herbal‐medico in wound repair: An incisive review

U Das, SS Behera, K Pramanik - Phytotherapy Research, 2017 - Wiley Online Library
Wound healing/cicatrization is a complex series of intricate processes that involve renewal
of skin/epidermis after injury. A large number of ethno‐medicinal plants/plant extracts are …

Diagnostic utility of HLA‐B* 5801 screening in severe allopurinol hypersensitivity syndrome: an updated systematic review and meta‐analysis

KH Yu, CY Yu, YF Fang - International journal of rheumatic …, 2017 - Wiley Online Library
Background Despite many studies suggesting an association between human leukocyte
antigen (HLA)‐B* 5801 and allopurinol‐induced toxic epidermal necrolysis (TEN) and …

HLA‐B* 15: 02 association with carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in an I ndian population: a pooled‐data analysis …

AHP Khor, KS Lim, CT Tan, SM Wong, CC Ng - Epilepsia, 2014 - Wiley Online Library
This study aimed to investigate the prevalence and association of HLA‐B* 15: 02 with
carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis (CBZ …

Integrating real‐world data in cost‐effectiveness analysis of universal HLA‐B*15:02 screening in Malaysia

HY Chong, KS Lim, SL Fong… - British Journal of …, 2023 - Wiley Online Library
Aims Despite the availability of newer antiseizure medications, carbamazepine (CBZ)
remains the gold standard. However, patients of Asian ancestry are susceptible to CBZ …