Tight junctions as a key for pathogens invasion in intestinal epithelial cells

T Paradis, H Bègue, L Basmaciyan, F Dalle… - International journal of …, 2021 - mdpi.com
Tight junctions play a major role in maintaining the integrity and impermeability of the
intestinal barrier. As such, they act as an ideal target for pathogens to promote their …

An up-date on Giardia and giardiasis

E Einarsson, S Ma'ayeh, SG Svärd - Current opinion in microbiology, 2016 - Elsevier
Highlights•Giardiasis is a multifactorial diarrheal disease.•Giardia infection can be protective
against other diarrheal diseases.•Giardia infection can induce IBS and chronic fatigue …

[HTML][HTML] Advances in understanding Giardia: determinants and mechanisms of chronic sequelae

LA Bartelt, RB Sartor - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Giardia lamblia is a flagellated protozoan that is the most common cause of intestinal
parasitic infection in children living in resource-limited settings. The pathogenicity of Giardia …

Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

SY Ma'ayeh, J Liu, D Peirasmaki… - PLoS neglected …, 2017 - journals.plos.org
Background Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis
in humans, the most common form of parasite-induced diarrhea. Disease mechanisms are …

Pathogenesis and post-infectious complications in giardiasis

T Allain, AG Buret - Advances in parasitology, 2020 - Elsevier
Giardia is an important cause of diarrhoea, and results in post-infectious and extra-intestinal
complications. This chapter presents a state-of-the art of our understanding of how this …

Comparative Pathobiology of the Intestinal Protozoan Parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum

A Hemphill, N Müller, J Müller - Pathogens, 2019 - mdpi.com
Protozoan parasites can infect the human intestinal tract causing serious diseases. In the
following article, we focused on the three most prominent intestinal protozoan pathogens …

Germ‐free mice as a model to study effect of gut microbiota on host physiology

M Grover, PC Kashyap - Neurogastroenterology & Motility, 2014 - Wiley Online Library
The alterations in resident gut microbiota seen in chronic gastrointestinal disorders have led
to an increasing interest in the role of gut bacteria in maintaining intestinal barrier function …

Interactions of Giardia sp. with the intestinal barrier: Epithelium, mucus, and microbiota

T Allain, CB Amat, JP Motta, A Manko, AG Buret - Tissue Barriers, 2017 - Taylor & Francis
Understanding how intestinal enteropathogens cause acute and chronic alterations has
direct animal and human health perspectives. Significant advances have been made on this …

Microvesicles released from Giardia intestinalis disturb host-pathogen response in vitro

I Evans-Osses, A Mojoli, M Monguió-Tortajada… - European journal of cell …, 2017 - Elsevier
Giardia intestinalis (GI), is an anaerobic protozoan and the aetiological agent of giardiasis, a
diarrhoea present worldwide and associated with poverty. GI has a simple life cycle …

Infection strategies of intestinal parasite pathogens and host cell responses

BM Di Genova, RR Tonelli - Frontiers in microbiology, 2016 - frontiersin.org
Giardia lamblia, Cryptosporidium sp., and Entamoeba histolytica are important pathogenic
intestinal parasites and are amongst the leading causes worldwide of diarrheal illness in …