SA Gomez-Ochoa, M Pitton, LG Valente… - The Lancet …, 2022 - thelancet.com
Background Antimicrobial resistance of bacterial pathogens is an increasing clinical problem and alternative approaches to antibiotic chemotherapy are needed. One of these …
N Pal, P Sharma, M Kumawat, S Singh… - Infectious …, 2024 - Taylor & Francis
The increasing global incidence of multidrug-resistant (MDR) bacterial infections threatens public health and compromises various aspects of modern medicine. Recognising the …
G Dhungana, R Nepal, M Regmi… - Frontiers in Cellular and …, 2021 - frontiersin.org
Phage therapy is one of the most promising alternatives to antibiotics as we face global antibiotic resistance crisis. However, the pharmacokinetics (PK) and pharmacodynamics …
The mosquito microbiota has a profound impact on multiple biological processes ranging from reproduction to disease transmission. Interestingly, the adult mosquito microbiota is …
The recent approval of experimental phage therapies by the FDA and other regulatory bodies with expanded access in cases in the United States and other nations caught the …
R Nepal, G Houtak, S Karki, G Dhungana… - Archives of …, 2022 - Springer
Application of bacteriophages (phages) to treat complex multidrug-resistant bacterial infection is gaining traction because of its efficacy and universal availability. However, as …
Phage therapy has recently been revitalized in the West with many successful applications against multi-drug-resistant bacterial infections. However, the lack of geographically diverse …
A Maharjan, R Nepal, G Dhungana, A Parajuli… - 2021 - elibrary.nhrc.gov.np
Background: Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen frequently causing healthcare-associated infections. The apocalyptic rise of antimicrobial …
Klebsiella pneumoniae is an opportunistic pathogen involved in both hospital-and community-acquired infections. K. pneumoniae is associated with various infections …