Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering
Proprotein convertase subtilisin kexin 9 (PCSK9) is a key regulator of low-density lipoprotein
receptor levels and LDL-cholesterol levels. Loss-of-function mutations in PCSK9 gene are …
receptor levels and LDL-cholesterol levels. Loss-of-function mutations in PCSK9 gene are …
Prevention and endothelial therapy of coronary artery disease
M Barton - Current opinion in pharmacology, 2013 - Elsevier
Functional integrity of endothelial cells is an indicator and a prerequisite for vascular health
and counteracts the development of atherosclerosis. This concept of 'endothelial …
and counteracts the development of atherosclerosis. This concept of 'endothelial …
Monocyte to HDL ratio: A novel marker of resistant hypertension in CKD patients
Background Inflammation, oxidative stress (OS), atherosclerosis and resistant hypertension
(RH) are common features of chronic kidney disease (CKD) leading to a higher risk of death …
(RH) are common features of chronic kidney disease (CKD) leading to a higher risk of death …
Emerging roles of IL-33/ST2 axis in renal diseases
Renal diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD), have
a great impact on health care systems worldwide. Similar to cardiovascular diseases, renal …
a great impact on health care systems worldwide. Similar to cardiovascular diseases, renal …
New perspectives on CKD-induced dyslipidemia
M Bermúdez-López, D Arroyo, À Betriu… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Chronic kidney disease (CKD) is a world-wide health concern associated with
a significantly higher cardiovascular morbidity and mortality. One of the principal …
a significantly higher cardiovascular morbidity and mortality. One of the principal …
[HTML][HTML] Renal systems biology of patients with systemic inflammatory response syndrome
A systems biology approach was used to comprehensively examine the impact of renal
disease and hemodialysis (HD) on patient response during critical illness. To achieve this …
disease and hemodialysis (HD) on patient response during critical illness. To achieve this …
Angiotensin II-induced early and late inflammatory responses through NOXs and MAPK pathways
X Zhang, J Yang, X Yu, S Cheng, H Gan, Y Xia - Inflammation, 2017 - Springer
Abstract Angiotensin II (Ang II) dysregulation has been determined as cause or an effect of
many diseases. The relationship between Ang II and reactive oxygen species (ROS), which …
many diseases. The relationship between Ang II and reactive oxygen species (ROS), which …
Dimethylamine enhances platelet hyperactivity in chronic kidney disease model
Y Gao, J Zhang, H Chen, Z Wang, J Hou… - Journal of Bioenergetics …, 2021 - Springer
Chronic kidney disease (CKD) remains a major health threat worldwide which is associated
with elevated blood level of dimethylamine (DMA) and unbalanced platelet functions …
with elevated blood level of dimethylamine (DMA) and unbalanced platelet functions …
[PDF][PDF] How do we manage coronary artery disease in patients with CKD and ESRD?
HY Choi, HC Park, SK Ha - … & Blood Pressure: E & BP, 2014 - synapse.koreamed.org
Chronic kidney disease (CKD) has been shown to be an independent risk factor for
cardiovascular events. In addition, patients with pre-dialysis CKD appear to be more likely to …
cardiovascular events. In addition, patients with pre-dialysis CKD appear to be more likely to …
[HTML][HTML] The impact of preoperative chronic kidney disease on outcomes after Crawford extent II thoracoabdominal aortic aneurysm repairs
JS Coselli, HS Amarasekara, Q Zhang… - The Journal of Thoracic …, 2018 - Elsevier
Objective To determine whether preoperative chronic kidney disease (CKD) is predictive of
poor outcomes in patients who undergo Crawford extent II thoracoabdominal aortic …
poor outcomes in patients who undergo Crawford extent II thoracoabdominal aortic …