Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship
P Prasher, R Fatima, M Sharma, B Tynybekov… - Chemico-biological …, 2023 - Elsevier
Lignans are plant-derived polyphenolic compounds with a plethora of biological
applications. Also, regarded as phytoestrogens, the lignans offer a variety of health benefits …
applications. Also, regarded as phytoestrogens, the lignans offer a variety of health benefits …
[HTML][HTML] Advances in neovascularization after diabetic ischemia
Y Cai, GY Zang, Y Huang, Z Sun, LL Zhang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
With the high incidence of diabetes around the world, ischemic complications cause a
serious influence on people's production and living. Neovascularization plays a significant …
serious influence on people's production and living. Neovascularization plays a significant …
Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based …
Y Li, X Peng, G Wang, B Zan, Y Wang, J Zou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance In Traditional Chinese Medicine (TCM),
cholestasis liver disease belongs to jaundice. Yinchenzhufu decoction (YCZFD) is a classic …
cholestasis liver disease belongs to jaundice. Yinchenzhufu decoction (YCZFD) is a classic …
p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in …
Recently, phosphodiesterases (PDEs) have gained great attention due to their implication in
Parkinson's disease (PD) pathogenesis. Noteworthy, the PDE4 enzyme is highly expressed …
Parkinson's disease (PD) pathogenesis. Noteworthy, the PDE4 enzyme is highly expressed …
Hypothalamic paraventricular nucleus hydrogen sulfide exerts antihypertensive effects in spontaneously hypertensive rats via the Nrf2 pathway
WJ Xia, KL Liu, XM Wang, Y Yang… - American journal of …, 2023 - academic.oup.com
Abstract Background Hydrogen sulfide (H2S) is widely distributed throughout the nervous
system with various antioxidant and anti-inflammatory properties. Hypertension involves an …
system with various antioxidant and anti-inflammatory properties. Hypertension involves an …
Metabolic characteristics of voriconazole–Induced liver injury in rats
Q Du, M Teng, L Yang, C Meng, Y Qiu, C Wang… - Chemico-Biological …, 2023 - Elsevier
Voriconazole (VOR)–induced liver injury is a common adverse reaction, and can lead to
serious clinical outcomes. It is of great significance to describe the metabolic characteristics …
serious clinical outcomes. It is of great significance to describe the metabolic characteristics …
Aqueous extract of Epimedium sagittatum (Sieb. et Zucc.) Maxim. induces liver injury in mice via pyroptosis
L Song, D Wang, Y Zhai, X Zhang, Y Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Epimedium sagittatum (Sieb. et Zucc.) Maxim. has
been used traditionally in Asia. It can dispel wind and cold, tonify the kidney, and strengthen …
been used traditionally in Asia. It can dispel wind and cold, tonify the kidney, and strengthen …
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis
W Wang, S Chen, S Xu, G Liao, W Li, X Yang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Jianpi Shengqing Huazhuo Formula (JSH) is a
modified prescription based on traditional Chinese medicine theory and classic …
modified prescription based on traditional Chinese medicine theory and classic …
Multi-omics analysis of lung tissue metabolome and proteome reveals the therapeutic effect of Shegan Mahuang Decoction against asthma in rats
Y Sun, Y Han, W Guo, X Xu, L Zhao, J Yang, L Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Shegan Mahuang Decoction (SMD) is a classic
traditional Chinese medicine (TCM) formula for asthma treatment, but the anti-asthma …
traditional Chinese medicine (TCM) formula for asthma treatment, but the anti-asthma …
Selective CDK9 knockdown sensitizes TRAIL response by suppression of antiapoptotic factors and NF-kappaB pathway
Q Yuan, K Su, S Li, X Long, L Liu, J Sun, X Yuan… - Apoptosis, 2023 - Springer
The aberrantly up-regulated CDK9 can be targeted for cancer therapy. The CDK inhibitor
dinaciclib (Dina) has been found to drastically sensitizes cancer response to TRAIL …
dinaciclib (Dina) has been found to drastically sensitizes cancer response to TRAIL …