Clostridium difficile infection

J Czepiel, M Dróżdż, H Pituch, EJ Kuijper… - European Journal of …, 2019 - Springer
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

Faecal microbiota transplantation for recurrent Clostridioides difficile infection: an updated systematic review and meta-analysis

SMD Baunwall, MM Lee, MK Eriksen, BH Mullish… - …, 2020 - thelancet.com
Background Faecal microbiota transplantation (FMT) is effective for recurrent Clostridioides
difficile infection (CDI), but inconsistent effect rates and uncertain evidence levels have …

[HTML][HTML] Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation

ZH Shen, CX Zhu, YS Quan, ZY Yang… - World journal of …, 2018 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) is an inflammatory disease that mainly affects the colon and rectum. It
is believed that genetic factors, host immune system disorders, intestinal microbiota …

Systematic review with meta‐analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection

MN Quraishi, M Widlak, N Bhala… - Alimentary …, 2017 - Wiley Online Library
Background Clostridium difficile infection (CDI) is the commonest nosocomial cause of
diarrhoea. Faecal microbiota transplantation (FMT) is an approved treatment for recurrent or …

Systematic review: adverse events of fecal microbiota transplantation

S Wang, M Xu, W Wang, X Cao, M Piao, S Khan, F Yan… - PloS one, 2016 - journals.plos.org
Background Fecal microbiota transplantation (FMT) is a microbiota-based therapy that
shows therapeutic potential in recurrent or refractory Clostridium difficile infections and other …

Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook

CR Kelly, S Kahn, P Kashyap, L Laine, D Rubin… - Gastroenterology, 2015 - Elsevier
The community of microorganisms within the human gut (or microbiota) is critical to health
and functions with a level of complexity comparable to that of an organ system. Alterations of …

Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection

I Youngster, GH Russell, C Pindar, T Ziv-Baran, J Sauk… - Jama, 2014 - jamanetwork.com
Importance Fecal microbiota transplantation (FMT) has been shown to be effective in
treating relapsing or refractoryClostridium difficileinfection, but practical barriers and safety …

Fecal Microbiota Transplantation for Clostridium difficile Infection: A Systematic Review

D Drekonja, J Reich, S Gezahegn, N Greer… - Annals of internal …, 2015 - acpjournals.org
Background: The role of fecal microbiota transplantation (FMT) for Clostridium difficile
infection (CDI) is not well-known. Purpose: To assess the efficacy, comparative …

Synergistic bacterial compositions and methods of production and use thereof

MR Henn, G Von Maltzahn, AM D'onofrio… - US Patent …, 2015 - Google Patents
2014-04-08 Assigned to Seres Health, Inc. reassignment Seres Health, Inc. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: AFEYAN …

The human gut microbiome in health: establishment and resilience of microbiota over a lifetime

K Greenhalgh, KM Meyer, KM Aagaard… - Environmental …, 2016 - Wiley Online Library
With technological advances in culture‐independent molecular methods, we are uncovering
a new facet of our natural history by accounting for the vast diversity of microbial life which …