Novel drug delivery systems (NDDS) delivered the active molecules to the target site in a
defined manner for produce the desired effects without disturbing the delicate bio …

Human le ishmaniasis is a vector-borne, neglected infectious disease that is widely
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …

A novel electrosynthetic protocol for the direct conversion of easily accessible 4-
hydroxybenzaldehydes into valuable benzoquinones is reported. The transformation is …

Highlights•Visceral leishmaniasis is a fatal infectious disease caused by protozoan
parasite.•Current antileishmanial drugs are inefficient for treatment of leishmaniasis.•There …

To develop and test new therapeutics and immune prophylaxis strategies for visceral
leishmaniasis (VL), understanding tissue parasitism evolution after experimental infection …

Objectives: Establishment of a mouse model for congenital toxoplasmosis based on oral
infection with oocysts from Toxoplasma gondii ME49 and its application for investigating …

Introduction: The armamentarium of antileishmanial drugs is small. It is further being
threatened by the development of resistance and decreasing sensitivity to the available …

Infectious diseases caused by pathogenic protozoa are among the most significant causes
of death in humans. Therapeutic options are scarce and massively challenged by the …

Leishmaniasis, a neglected tropical disease, is prevalent in 98 countries with the occurrence
of 1.3 million new cases annually. The conventional therapy for visceral leishmaniasis …

Quinones and their corresponding hydroquinone congeners are chemical moieties with an
utmost relevance in nature and industry alike. 1− 4 Quinones exhibit a cyclic dione structure …