Cyclic decidualization of the human endometrium in reproductive health and failure

B Gellersen, JJ Brosens - Endocrine reviews, 2014 - academic.oup.com
Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

What can we learn from rodents about prolactin in humans?

N Ben-Jonathan, CR LaPensee… - Endocrine …, 2008 - academic.oup.com
Abstract Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …

The myometrial junctional zone spiral arteries in normal and abnormal pregnancies: a review of the literature

JJ Brosens, R Pijnenborg, IA Brosens - American journal of obstetrics and …, 2002 - Elsevier
Deep placentation in the human requires physiologic transformation of the spiral arteries
into uteroplacental vessels. This process involves the inner myometrial segment (junctional …

Minireview: extrapituitary prolactin: an update on the distribution, regulation, and functions

RJ Marano, N Ben-Jonathan - Molecular endocrinology, 2014 - academic.oup.com
Prolactin (PRL) is an important hormone with many diverse functions. Although it is
predominantly produced by lactrotrophs of the pituitary there are a number of other organs …

Uterine cyclin A2–deficient mice as a model of female early pregnancy loss

F Aljubran, K Schumacher, A Graham… - The Journal of Clinical …, 2024 - jci.org
Proper action of the female sex steroids 17β-estradiol (E2) and progesterone (P4) on the
endometrium is essential for fertility. Beyond its role in regulating the cell cycle, cyclin A2 …

Adipocyte prolactin: regulation of release and putative functions

T Brandebourg, E Hugo… - Diabetes, Obesity and …, 2007 - Wiley Online Library
Pituitary‐derived prolactin (PRL) is a well‐known regulator of the lactating mammary gland.
However, the recent discovery that human adipose tissue produces PRL as well as …

Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells

EC Mazur, YM Vasquez, X Li, R Kommagani… - …, 2015 - academic.oup.com
Decidualization is a complex process involving cellular proliferation and differentiation of the
endometrial stroma that is required to establish and support pregnancy. Progesterone acting …

Prolactin (PRL) in adipose tissue: regulation and functions

N Ben-Jonathan, E Hugo - Recent Advances in Prolactin Research, 2014 - Springer
New information concerning the effects of prolactin (PRL) on metabolic processes warrants
reevaluation of its overall metabolic actions. PRL affects metabolic homeostasis by …

Autocrine/paracrine roles of extrapituitary growth hormone and prolactin in health and disease: An overview

S Harvey, CG Martínez-Moreno, M Luna… - General and …, 2015 - Elsevier
Growth hormone (GH) and prolactin (PRL) are both endocrines that are synthesized and
released from the pituitary gland into systemic circulation. Both are therefore hormones and …

HoxA-11 and FOXO1A cooperate to regulate decidual prolactin expression: towards inferring the core transcriptional regulators of decidual genes

VJ Lynch, K Brayer, B Gellersen, GP Wagner - PloS one, 2009 - journals.plos.org
Background During the menstrual cycle, the ovarian steroid hormones estrogen and
progesterone control a dramatic transcriptional reprogramming of endometrial stromal cells …