Targeting bacterial phospholipids and their synthesis pathways for antibiotic discovery
M Song, S Chen, W Lin, K Zhu - Progress in Lipid Research, 2024 - Elsevier
Bacterial infections in humans and animals caused by multidrug-resistant (MDR) pathogens
pose a serious threat to public health. New antibacterial targets are extremely urgent to …
pose a serious threat to public health. New antibacterial targets are extremely urgent to …
Overlooked abiotic humification for kanamycin removal in kanamycin fermentation waste by tea polyphenols: New, environmentally friendly and specific
X Hui, Y Wang, H Zhang, W Fang, H Liu… - Chemical Engineering …, 2023 - Elsevier
Kanamycin, a typical aminoglycoside antibiotic, is mainly used for the treatment of diseases
in humans or animals, while the related antibiotic pollution has been regarded as a serious …
in humans or animals, while the related antibiotic pollution has been regarded as a serious …
Translation fidelity and respiration deficits in CLPP-deficient tissues: mechanistic insights from mitochondrial complexome profiling
J Key, S Gispert, G Koepf, J Steinhoff-Wagner… - International journal of …, 2023 - mdpi.com
The mitochondrial matrix peptidase CLPP is crucial during cell stress. Its loss causes
Perrault syndrome type 3 (PRLTS3) with infertility, neurodegeneration, and a growth deficit …
Perrault syndrome type 3 (PRLTS3) with infertility, neurodegeneration, and a growth deficit …
Bioenergetic state of Escherichia coli controls aminoglycoside susceptibility
JY El Khoury, J Zamarreño Beas, A Huguenot, B Py… - Mbio, 2023 - Am Soc Microbiol
Aminoglycosides (AG) have been used against Gram-negative bacteria for decades. Yet,
how bacterial metabolism and environmental conditions modify AG toxicity is poorly …
how bacterial metabolism and environmental conditions modify AG toxicity is poorly …
The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme
V Bhandari, SE Reichheld, S Houliston… - Journal of Biological …, 2023 - ASBMB
Regulatory ATPase variant A (RavA) is a MoxR AAA+ protein that functions together with a
partner protein termed von Willebrand factor type A interacting with AAA+ ATPase (ViaA) …
partner protein termed von Willebrand factor type A interacting with AAA+ ATPase (ViaA) …
RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae
E Krin, A Carvalho, M Lang, A Babosan… - Microbiology …, 2023 - Am Soc Microbiol
RavA-ViaA were reported to play a role in aminoglycoside (AG) sensitivity, but the
mechanisms remain elusive. Here, we performed competition and survival experiments to …
mechanisms remain elusive. Here, we performed competition and survival experiments to …
RavA-ViaA links Vibrio cholerae Cpx- and Zra2- envelope stress to antibiotic response
E Krin, A Carvalho, M Lang, A Babosan, D Mazel… - bioRxiv, 2023 - biorxiv.org
RavA-ViaA were reported to play a role in aminoglycoside sensitivity but the mechanisms
remain elusive. Here, we performed competition and survival experiments to confirm that …
remain elusive. Here, we performed competition and survival experiments to confirm that …