Autism spectrum disorder (ASD) is one of the most complex behavioral disorders with a
strong genetic influence. The objectives of this article are to review the current status of …

Inhibition of the protease β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is a
promising treatment strategy for Alzheimer's disease, and a number of BACE inhibitors are …

Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder
characterized by age-inappropriate symptoms of inattention, impulsivity, and hyperactivity …

Unlike their wolf ancestors, dogs have unique social skills for communicating and
cooperating with humans. Previously, significant heritabilities for human-directed social …

The Sez6 family consists of Sez6, Sez6L, and Sez6L2. Its members are expressed
throughout the brain and have been shown to influence synapse numbers and dendritic …

Autosomal recessive nonsyndromic hearing loss is a genetically heterogeneous disorder.
Here, we report a severe-to-profound sensorineural hearing loss locus, DFNB100 on …

Background: The sperm DNA methylation landscape is unique and critical for offspring
health. If gamete-derived DNA methylation escapes reprograming in early embryos …

Autism is a complex genetic disorder where both de‐novo and inherited genetics factors
play a role. Next generation sequencing approaches have been extensively used to identify …

Background Disco-interacting protein 2 C (DIP2C) has recently been reported as a new
susceptibility gene for autism spectrum disorder (ASD) in a genome-wide association study …

Aim Severe mental illnesses (SMI), such as bipolar disorder and schizophrenia, are highly
heritable, and have a complex pattern of inheritance. Genome‐wide association studies …