The potential of selected agri-food loss and waste to contribute to a circular economy: Applications in the food, cosmetic and pharmaceutical industries

LLDR Osorio, E Flórez-López, CD Grande-Tovar - Molecules, 2021 - mdpi.com
The food sector includes several large industries such as canned food, pasta, flour, frozen
products, and beverages. Those industries transform agricultural raw materials into added …

New insights in to the intrinsic and acquired drug resistance mechanisms in mycobacteria

MJ Nasiri, M Haeili, M Ghazi, H Goudarzi… - Frontiers in …, 2017 - frontiersin.org
Infectious diseases caused by clinically important Mycobacteria continue to be an important
public health problem worldwide primarily due to emergence of drug resistance crisis. In …

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

D Machado, TS Coelho, J Perdigao, C Pereira… - Frontiers in …, 2017 - frontiersin.org
Numerous studies show efflux as a universal bacterial mechanism contributing to antibiotic
resistance and also that the activity of the antibiotics subject to efflux can be enhanced by …

Actionable mechanisms of drug tolerance and resistance in Mycobacterium tuberculosis

D Datta, S Jamwal, N Jyoti, S Patnaik… - The FEBS …, 2024 - Wiley Online Library
The emergence of antimicrobial resistance (AMR) across bacterial pathogens presents a
serious threat to global health. This threat is further exacerbated in tuberculosis (TB), mainly …

Expression analysis of 10 efflux pump genes in multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis clinical isolates

J Kardan-Yamchi, H Kazemian, M Haeili… - Journal of Global …, 2019 - Elsevier
Objectives Active extrusion of antituberculosis drugs via efflux pumps (EPs) has been
suggested as contributing to drug resistance in Mycobacterium tuberculosis. This study was …

Acyldepsipeptide analogues: a future generation antibiotics for tuberculosis treatment

SZZ Cobongela, MM Makatini, PS Mdluli, NRS Sibuyi - Pharmaceutics, 2022 - mdpi.com
Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs),
which are currently explored for treatment of pathogenic infections, including tuberculosis …

Single nucleotide polymorphisms in efflux pumps genes in extensively drug resistant Mycobacterium tuberculosis isolates from Pakistan

A Kanji, R Hasan, A Ali, A Zaver, Y Zhang, K Imtiaz… - Tuberculosis, 2017 - Elsevier
It is challenging to understand mechanisms of drug resistance in Mycobacterium
tuberculosis (MTB) due to the large variability in resistance associated genes. Efflux pump …

Detection and characterization of mutations in genes related to isoniazid resistance in Mycobacterium tuberculosis clinical isolates from Iran

P Bakhtiyariniya, AD Khosravi, M Hashemzadeh… - Molecular biology …, 2022 - Springer
Background The global rise in drug-resistant Mycobacterium tuberculosis (M. tb), and
especially the significant prevalence of isoniazid (INH)-resistance constitute a significant …

Efficacy of line probe assay in detection of drug-resistant pulmonary tuberculosis in comparison with GeneXpert and phenotypic methods in Iran and genetic analysis …

H Kazemian, J Kardan-Yamchi, A Bahador… - Infection and drug …, 2019 - Taylor & Francis
Background Successful treatment of tuberculosis depends on early diagnosis and use of
appropriate drug susceptibility testing in a timely manner. In the present study, LPA efficacy …

Prevalence of Beijing and Haarlem genotypes among multidrug-resistant Mycobacterium tuberculosis in Iran: systematic review and meta-analysis

S Tarashi, A Fateh, FR Jamnani, SD Siadat, F Vaziri - Tuberculosis, 2017 - Elsevier
Antimicrobial drug resistance creates major problems in the control of tuberculosis (TB).
Beijing and Haarlem genotypes of Mycobacterium tuberculosis are the prevalent genotypes …