Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …

Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …

Background & Aims Wilson disease (WD) is an inherited disorder of copper metabolism that
leads to copper accumulation and toxicity in the liver and brain. It is caused by mutations in …

Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

Several diseases share misfolding of different peptides and proteins as a key feature for
their development. This is the case of important neurodegenerative diseases such as …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

A “turn-on” fluorescent probe based on amino-functionalized metal-organic frameworks
(MOF-5-NH 2) is developed for the detection of Cu 2+, Pb 2+ and pyrophosphate (P 2 O 7 …

Parkinson's disease is the second most common neurodegenerative disorder worldwide.
Neurodegeneration in this pathology is characterized by the loss of dopaminergic neurons …

Olfactory dysfunction is one of the early symptoms seen in Parkinson's disease (PD).
However, the mechanisms underlying olfactory pathology that impacts PD disease …

Autophagy generally refers to cell catabolic and recycling process in which cytoplasmic
components are delivered to lysosomes for degradation. During the last two decades …