Ocular drug delivery: a comprehensive review
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
Bilosomes as promising nanovesicular carriers for improved transdermal delivery: construction, in vitro optimization, ex vivo permeation and in vivo evaluation
Purpose The goal of this research was to enhance the transdermal delivery of lornoxicam
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …
[HTML][HTML] RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential …
SF Elhabal, SA Ghaffar, R Hager, NA Elzohairy… - 2023 - Elsevier
[email protected](MH Elkomy),[email protected](MA Khasawneh). Contents lists available at
ScienceDirect International Journal of Pharmaceutics: X journal homepage: www …
ScienceDirect International Journal of Pharmaceutics: X journal homepage: www …
Formulation and evaluation of cubosomes drug delivery system for treatment of glaucoma: Ex-vivo permeation and in-vivo pharmacodynamic study
Glaucoma, a chronic disease of elevated intraocular pressure, is considered as the first
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …
Corneal targeted Sertaconazole nitrate loaded cubosomes: preparation, statistical optimization, in vitro characterization, ex vivo permeation and in vivo studies
NF Younes, SA Abdel-Halim, AI Elassasy - International journal of …, 2018 - Elsevier
Sertaconazole nitrate (STZ) is a poorly soluble antifungal drug commonly used for treating
fungal skin infections. Introducing it as a new treatment option for the management of fungal …
fungal skin infections. Introducing it as a new treatment option for the management of fungal …
Central composite optimization of ocular mucoadhesive cubosomes for enhanced bioavailability and controlled delivery of voriconazole
This study aimed to formulate and statistically optimize cubosomal formulations loaded with
voriconazole to enhance and control its ocular bioavailability. The independent variables of …
voriconazole to enhance and control its ocular bioavailability. The independent variables of …
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
Development and optimization of terpene-enriched vesicles (Terpesomes) for effective ocular delivery of fenticonazole nitrate: in vitro characterization and in vivo …
Objective The aim of the current study was to load fenticonazole nitrate, a slightly water-
soluble antifungal agent, into terpene-enriched phospholipid vesicles (terpesomes) as a …
soluble antifungal agent, into terpene-enriched phospholipid vesicles (terpesomes) as a …
Tailoring terpesomes and leciplex for the effective ocular conveyance of moxifloxacin hydrochloride (Comparative assessment): in-vitro, ex-vivo, and in-vivo evaluation
Aim To compare the ability of both terpesomes (TPs) and leciplex (LPs) loaded moxifloxacin
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …
Formulation and optimization of cationic nanoemulsions for enhanced ocular delivery of dorzolamide hydrochloride using Box-Behnken design: In vitro and in vivo …
The present study was designed to develop dorzolamide HCl (DRZ) loaded cationic
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …