Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …

Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

Glutamate is the major excitatory neurotransmitter in the brain and may be a key
neurotransmitter involved in autism. Literature pertaining to glutamate and autism or related …

In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …

Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …

The analysis of animal models of neurological disease has been instrumental in furthering
our understanding of neurodevelopment and brain diseases. However, animal models are …

Social interaction is a complex behavior which requires the individual to integrate various
internal processes, such as social motivation, social recognition, salience, reward, and …

Autism spectrum disorder (ASD) comprises a range of neurological conditions that affect
individuals' ability to communicate and interact with others. People with ASD often exhibit …

Short trinucleotide expansions at the FMR1 locus are associated with the late-onset
condition fragile X-associated tremor/ataxia syndrome (FXTAS), which shows very different …