In the past decade, evidence for a fluid clearance pathway in the central nervous system
known as the glymphatic system has grown. According to the glymphatic system concept …

The functions of the glymphatic system include clearance of the metabolic waste and
modulation of the water transport in the brain, and it forms a brain-wide fluid network along …

Objective This study was undertaken to investigate migraine glymphatic and meningeal
lymphatic vessel (mLV) functions. Methods Migraine patients and healthy controls (HCs) …

Cerebrospinal fluid (CSF) flows through the central nervous system (CNS) via the
glymphatic pathway to clear the interstitium of metabolic waste. In preclinical studies …

Earlier studies based on 2-photon imaging have shown that glymphatic cerebrospinal fluid
(CSF) transport is regulated by the sleep-wake cycle. To examine this association, we used …

This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

The heart is a functional syncytium controlled by a delicate and sophisticated balance
ensured by the tight coordination of its several cell subpopulations. Accordingly …

As a highly selective and semi-permeable barrier that separates the circulating blood from
the brain and central nervous system (CNS), the blood-brain barrier (BBB) plays a critical …

This review focuses on the physiology of glymphatic solute transport and waste clearance,
using evidence from experimental animal models as well as from human studies. Specific …

Calcium channel blockers (CCBs) differ in their ability to penetrate into the brain.
Pharmacoepidemiological studies suggest that CCBs as a class may have beneficial effects …