Nose to brain drug delivery-a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion

Y Long, Q Yang, Y Xiang, Y Zhang, J Wan, S Liu… - Pharmacological …, 2020 - Elsevier
Cerebral ischemia reperfusion injury (CIRI), one of the major causes of death from stroke in
the world, not only causes tremendous damage to human health, but also brings heavy …

Bridging thrombolysis achieved better outcomes than direct thrombectomy after large vessel occlusion: an updated meta-analysis

Y Wang, X Wu, C Zhu, M Mossa-Basha, A Malhotra - Stroke, 2021 - Am Heart Assoc
The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

Endovascular thrombectomy with or without intravenous alteplase in acute stroke

P Yang, Y Zhang, L Zhang, Y Zhang… - … England Journal of …, 2020 - Mass Medical Soc
Background In acute ischemic stroke, there is uncertainty regarding the benefit and risk of
administering intravenous alteplase before endovascular thrombectomy. Methods We …

European Stroke Organisation (ESO)–European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for …

G Turc, G Tsivgoulis, HJ Audebert… - Journal of …, 2022 - jnis.bmj.com
Six randomized controlled clinical trials have assessed whether mechanical thrombectomy
(MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT within 4.5 hours of …

European Stroke Organisation–European Society for Minimally Invasive Neurological Therapy expedited recommendation on indication for intravenous thrombolysis …

G Turc, G Tsivgoulis, HJ Audebert… - European Stroke …, 2022 - journals.sagepub.com
Six randomized controlled clinical trials have assessed whether mechanical thrombectomy
(MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT within 4.5 hours of …

Intravenous thrombolysis prior to mechanical thrombectomy in large vessel occlusions

AH Katsanos, K Malhotra, N Goyal, A Arthur… - Annals of …, 2019 - Wiley Online Library
Objective The substantial clinical improvement in acute ischemic stroke (AIS) patients
treated with mechanical thrombectomy (MT), combined with the poor response of proximal …

Direct mechanical thrombectomy in tPA-ineligible and-eligible patients versus the bridging approach: a meta-analysis

J Kaesmacher, P Mordasini, M Arnold… - Journal of …, 2019 - jnis.bmj.com
Background Whether pretreatment with intravenous thrombolysis prior to mechanical
thrombectomy (IVT+ MTE) adds additional benefit over direct mechanical thrombectomy …

Acute ischaemic stroke: challenges for the intensivist

M Smith, U Reddy, C Robba, D Sharma… - Intensive care medicine, 2019 - Springer
Purpose To provide an update about the rapidly developing changes in the critical care
management of acute ischaemic stroke patients. Methods A narrative review was conducted …

Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of …

X Wang, Z Ye, JW Busse, MD Hill, EE Smith… - Stroke and Vascular …, 2022 - svn.bmj.com
Background Among patients who had an ischaemic stroke presenting directly to a stroke
centre where endovascular thrombectomy (EVT) is immediately available, there is …

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: a meta-analysis of randomized controlled trials

A Podlasek, PS Dhillon, W Butt… - … Journal of Stroke, 2021 - journals.sagepub.com
Background Direct mechanical thrombectomy may result in similar outcomes compared to a
bridging approach with intravenous thrombolysis (IVT+ MT) in acute ischemic stroke. Recent …