The risks of sarcopenia, falls and fractures in patients with type 2 diabetes mellitus

C Sarodnik, SPG Bours, NC Schaper… - Maturitas, 2018 - Elsevier
Fracture risk in patients with type 2 diabetes mellitus (T2DM) is increased, and the
mechanism is multifactorial. Recent research on T2DM-induced bone fragility shows that …

Careful use to minimize adverse events of oral antidiabetic medications in the elderly

AJ Scheen - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction An increasing number of older patients has type 2 diabetes treated with different
oral antidiabetic agents whose safety may raise concern considering some particularities of …

Diabetes in older people

GS Meneilly, A Knip, DB Miller, D Sherifali… - Canadian journal of …, 2018 - Elsevier
This guideline refers primarily to type 2 diabetes in the older person. There is limited
information on the management of type 1 diabetes in the elderly, but this is included …

Antihypertensive medications, loop diuretics, and risk of hip fracture in the elderly: a population-based cohort study of 81,617 Italian patients newly treated between …

G Corrao, P Mazzola, M Monzio Compagnoni, F Rea… - Drugs & aging, 2015 - Springer
Objective Our objective was to assess the relationship between antihypertensive drugs, loop
diuretics, and the risk of hospitalization for hip fracture (HF). Design We conducted a …

Sleep duration and sleep disturbances in association with falls among the middle-aged and older adults in China: a population-based nationwide study

SK Essien, CX Feng, W Sun, M Farag, L Li, Y Gao - BMC geriatrics, 2018 - Springer
Background Falls pose major health problems to the middle-aged and older adults and may
potentially lead to various levels of injuries. Sleep duration and disturbances have been …

Fracture risk in patients with newly diagnosed type 2 diabetes: a retrospective database analysis in primary care

W Rathmann, K Kostev - Journal of Diabetes and its Complications, 2015 - Elsevier
Aims It is unclear whether fracture risk is increased in newly diagnosed type 2 diabetes
patients. In addition, fracture risk of various sites (hip, spine, upper extremity) was analysed …

Long-term safety of dapagliflozin in older patients with type 2 diabetes mellitus: a pooled analysis of phase IIb/III studies

P Fioretto, TA Mansfield, A Ptaszynska, Y Yavin… - Drugs & aging, 2016 - Springer
Objective To evaluate the 104-week safety of dapagliflozin in older patients with type 2
diabetes mellitus. Methods Pooled analysis assessing general safety (nine phase III …

The social burden of hypoglycemia in the elderly

A Nicolucci, B Pintaudi, MC Rossi, R Messina, F Dotta… - Acta …, 2015 - Springer
Aims The study aimed to evaluate the frequency of episodes of symptomatic hypoglycemia
(SH) in elderly patients with type 2 diabetes and their impact on quality of life. Methods The …

Severe hypoglycemia is associated with high risk for falls in adults with type 1 diabetes

VN Shah, M Wu, N Foster, R Dhaliwal… - Archives of …, 2018 - Springer
We evaluated fall frequency and factors affecting falls among middle-aged and older adults
with type 1 diabetes (T1D) from T1D Exchange Registry. Twenty-nine percent of T1D …

Bone effects of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in patients with type 2 diabetes mellitus

TC Blevins, A Farooki - Postgraduate medicine, 2017 - Taylor & Francis
Canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor approved for the
treatment of type 2 diabetes mellitus (T2DM), lowers blood glucose by inhibiting renal …