[HTML][HTML] Infrapatellar fat pad/synovium complex in early-stage knee osteoarthritis: potential new target and source of therapeutic mesenchymal stem/stromal cells

DN Greif, D Kouroupis, CJ Murdock… - … in bioengineering and …, 2020 - frontiersin.org
The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …

[HTML][HTML] Therapeutic perspectives for inflammation and senescence in osteoarthritis using mesenchymal stem cells, mesenchymal stem cell-derived extracellular …

MG Rizzo, TM Best, J Huard, M Philippon, F Hornicek… - Cells, 2023 - mdpi.com
Osteoarthritis (OA) is the most common cause of disability worldwide among the elderly.
Alarmingly, the incidence of OA in individuals less than 40 years of age is rising, likely due to …

[HTML][HTML] Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone …

YH Chan, KN Ho, YC Lee, MJ Chou, WZ Lew… - Stem Cell Research & …, 2022 - Springer
Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

[HTML][HTML] Cd10-Bound human mesenchymal stem/stromal cell-derived small extracellular vesicles possess immunomodulatory cargo and maintain cartilage …

D Kouroupis, LD Kaplan, J Huard, TM Best - Cells, 2023 - mdpi.com
The onset and progression of human inflammatory joint diseases are strongly associated
with the activation of resident synovium/infrapatellar fat pad (IFP) pro-inflammatory and pain …

[HTML][HTML] CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp

L Ma, Z Huang, D Wu, X Kou, X Mao, S Shi - Stem Cell Research & …, 2021 - Springer
Background Human mesenchymal stem cells from dental pulp (hMSC-DP), including dental
pulp stem cells from permanent teeth and exfoliated deciduous teeth, possess unique MSC …

[HTML][HTML] Heterogeneity of in vitro expanded mesenchymal stromal cells and strategies to improve their therapeutic actions

L Olmedo-Moreno, Y Aguilera, C Baliña-Sánchez… - Pharmaceutics, 2022 - mdpi.com
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …

[HTML][HTML] CD146+ Endometrial-derived mesenchymal stem/stromal cell subpopulation possesses exosomal secretomes with strong immunomodulatory miRNA …

C Leñero, LD Kaplan, TM Best, D Kouroupis - Cells, 2022 - mdpi.com
The perivascular localization of endometrial mesenchymal stem/stromal cells (eMSC) allows
them to sense local and distant tissue damage, promoting tissue repair and healing. Our …

Strategies to enhance immunomodulatory properties and reduce heterogeneity in mesenchymal stromal cells during ex vivo expansion

A Srinivasan, P Sathiyanathan, L Yin, TM Liu, A Lam… - Cytotherapy, 2022 - Elsevier
Therapies using mesenchymal stromal cells (MSCs) to treat immune and inflammatory
conditions are now at an exciting stage of development, with many MSC-based products …

[HTML][HTML] A Review on Pathophysiology, and Molecular Mechanisms of Bacterial Chondronecrosis and Osteomyelitis in Commercial Broilers

VSR Choppa, WK Kim - Biomolecules, 2023 - mdpi.com
Modern day broilers have a great genetic potential to gain heavy bodyweights with a huge
metabolic demand prior to their fully mature ages. Moreover, this made the broilers prone to …

Chemokine assay matrix defines the potency of human bone marrow mesenchymal stromal cells

AJ Lipat, C Cottle, BM Pirlot, J Mitchell… - Stem Cells …, 2022 - academic.oup.com
Potency analysis of mesenchymal stromal cells (MSCs) is required for their use in advanced
clinical trials. Assay matrix strategy evaluating more than a single property of MSCs is an …