Glaucoma is defined by characteristic optic nerve damage and corresponding visual field
defects and is the leading cause of irreversible blindness in the world. Elevated intraocular …

Glaucoma is a clinically heterogeneous disease and the world's leading cause of
irreversible blindness. Therapeutic intervention can prevent blindness but relies on early …

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness
worldwide, disproportionately affects individuals of African ancestry. We conducted a …

Advancements in computational techniques have transformed glaucoma research, providing
a deeper understanding of genetics, disease mechanisms, and potential therapeutic targets …

Purpose: To review the progress in glaucoma genetics over the past 25 years, including the
identification of genes with varying contributions to the disease and the development of …

Purpose: To review the current evidence and concepts around screening for glaucoma.
Methods/Results: A group of glaucoma-focused clinician scientists drew on knowledge and …

Purpose To evaluate the association between localised vascular and retinal nerve fibre
layer (RNFL) loss and genetic risk for glaucoma and cardiovascular disease using polygenic …

Glaucoma is a leading cause of visual impairment and a significant public health concern,
but despite ongoing advances in our understanding of the disease, several important clinical …

Ophthalmology has been at the forefront of the medical application of big data. Often
harnessed with a machine learning approach, big data has demonstrated potential to …

Primary open angle glaucoma (POAG) is defined as a “genetically complex trait”, where
modifying factors act on a genetic predisposing background. For the majority of …