Abstract Background Coronavirus disease 2019 (COVID-19) is accompanied by activated
immune-inflammatory pathways and oxidative stress, which both induce indoleamine-2, 3 …

The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …

One of the major challenges currently faced by global health systems is the prolonged
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …

Introduction: Similar to what it has been reported with preceding viral epidemics (such as
MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human …

Introduction Severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) infection
triggers inflammatory clinical stages that affect the outcome of patients with coronavirus …

Despite intense investigation, the pathogenesis of COVID-19 and the newly defined long
COVID-19 syndrome are not fully understood. Increasing evidence has been provided of …

Severe manifestations of coronavirus disease 2019 (COVID-19) and mortality have been
associated with physiological alterations that provide insights into the pathogenesis of the …

This study investigated the association between COVID-19 infection and host metabolic
signatures as prognostic markers for disease severity and mortality. We enrolled 82 patients …

Sepsis is a life-threatening condition caused by a dysregulated host response to infection.
Despite continued efforts to understand the pathophysiology of sepsis, no effective therapies …

Background: In 2019, SARS-CoV-2, the novel coronavirus, entered the world scene,
presenting a global health crisis with a broad spectrum of clinical manifestations …