Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Neuroinflammation is an inflammatory response in the brain and spinal cord, which can
involve the activation of microglia and astrocytes. It is a common feature of many central …

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disorder,
caused by the degeneration of upper and lower motor neurons for which there is no truly …

Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a
progressive neurodegenerative disease that affects both upper and lower motor neurons …

Amyotrophic lateral sclerosis is the most common degenerative disorder of motor neurons in
adults. As there is no cure, thousands of individuals who are alive at present will succumb to …

It is becoming increasingly apparent that microglia, the immune cells of the CNS, and their
peripheral counterparts, macrophages, have a major role in normal physiology and …

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is an aggressive
motor neuron degenerative disease characterized by selective loss of both upper and lower …

Neuronal cell death is the main pathological feature of chronic neurodegenerative diseases
(NDs) such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral …

Mutations of Fused in sarcoma (FUS), a ribonucleoprotein involved in RNA metabolism,
have been found associated with both familial and sporadic cases of amyotrophic lateral …