New insights into the pathogenesis of Streptococcus pneumoniae–associated hemolytic uremic syndrome

RR Scobell, BS Kaplan, L Copelovitch - Pediatric nephrology, 2020 - Springer
The purpose of this review is to describe Streptococcus pneumoniae–associated hemolytic
uremic syndrome (P-HUS) with emphasis on new insights into the pathophysiology and …

[HTML][HTML] Sialic acid and platelet count regulation: Implications in immune thrombocytopenia

MM Lee‐Sundlov, L Rivadeneyra, H Falet… - Research and Practice …, 2022 - Elsevier
Platelets are blood components that survive in circulation for 7 to 10 days in humans. Thus,
platelet production by bone marrow (BM) megakaryocytes (MKs), and their removal from the …

Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count

MM Lee-Sundlov, RT Burns, TO Kim… - Blood, The Journal …, 2021 - ashpublications.org
Immune thrombocytopenia (ITP) is a platelet disorder. Pediatric and adult ITP have been
associated with sialic acid alterations, but the pathophysiology of ITP remains elusive, and …

Red blood cell Thomsen‐Friedenreich antigen expression and galectin‐3 plasma concentrations in Streptococcus pneumoniae–associated hemolytic uremic …

N Burin des Roziers, P Chadebech, G Bodivit… - …, 2015 - Wiley Online Library
Background Pneumococcal hemolytic uremic syndrome (P‐HUS) is a rare but severe
complication of invasive pneumococcal disease (IPD) in young children. Consensual …

[PDF][PDF] 幼儿红细胞T 抗原活化导致交叉配血不合分析

高昂, 李萌, 王晓卫, 王雅茹, 李亭 - 临床血液学杂志, 2022 - lcxyen.whuhzzs.com
检测和分析交叉配型中继发性侧向错配患儿的血清学样本. 采用ABO, RhD 血型鉴定, Coombs
试验, 交叉配型, 新生儿血浆和多发性凝集红细胞特异性试验. 结果发现儿童红细胞与新生儿血浆 …

Severe hemolysis after plasma transfusion in a neonate with necrotizing enterocolitis, Clostridium perfringens infection, and red blood cell T‐polyagglutination

J Moh‐Klaren, G Bodivit, M Jugie, P Chadebech… - …, 2017 - Wiley Online Library
BACKGROUND Red blood cell (RBC) Thomsen‐Friedenreich antigen exposure (T
activation) in infants with necrotizing enterocolitis (NEC) has occasionally been associated …

Immunization with pneumococcal neuraminidases NanA, NanB and NanC to generate neutralizing antibodies and to increase survival in mice

RP Janapatla, CL Chen, MH Hsu… - Journal of Medical …, 2018 - microbiologyresearch.org
Purpose. Pneumococcal virulence protein-based vaccines can provide serotype-
independent protection against pneumococcal infections. Many studies, including clinical …

Erythrocyte T‐antigen activation in children: Patient characteristics and the hemolytic risk of transfusion

C Jacquot, PP Pary, V Babu, E Belay… - Pediatric Blood & …, 2021 - Wiley Online Library
Background T‐antigen activation usually occurs upon red blood cell (RBC) membrane
cryptantigen exposure due to bacterial enzymes. Although uncommon, the condition is …

Thomsen-Friedenreich activation of erythrocytes in infants leads to cross-matching incompatibility

GAO Ang, LI Meng, W Xiaowei, W Yaru… - J Clin Hematol, 2022 - lcxyen.whuhzzs.com
To detect and analyze the serological samples of a child with secondary lateral mismatch in
cross matching. ABO and RhD blood group identification, Coombs test, cross matching test …

Defects in Sialylation Cause Glomerular Injury

L Richardson - 2017 - search.proquest.com
Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by hemolytic
anemia, thrombocytopenia, and renal impairment. Complement dysregulation is associated …