Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

In Alzheimer's disease (AD), early synaptic dysfunction is associated with the increased
oligomeric amyloid-beta peptide, which causes NMDAR-dependent synaptic depression …

NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca2+-
permeable component of excitatory neurotransmission in the central nervous system (CNS) …

NMDA receptors (NMDARs) are glutamate-gated ion channels and are crucial for neuronal
communication. NMDARs form tetrameric complexes that consist of several homologous …

The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Adolescence is defined as a transitional period between childhood and adulthood
characterized by changes in social interaction and acquisition of mature cognitive abilities …

The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …

The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …

N-methyl-d-aspartate receptors (NMDARs) are present at many excitatory glutamate
synapses in the central nervous system and display unique properties that depend on their …

N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptor,
which play a central role in learning, memory, and synaptic development. NMDARs are …