Towards an integrative approach to understanding the role of chemerin in human health and disease

JL Rourke, HJ Dranse, CJ Sinal - Obesity Reviews, 2013 - Wiley Online Library
Chemerin is an adipocyte‐secreted protein with autocrine/paracrine roles on adipose
development and function as well as endocrine roles in metabolism and immunity. Following …

What's new in our understanding of the role of adipokines in rheumatic diseases?

R Gómez, J Conde, M Scotece… - Nature Reviews …, 2011 - nature.com
Important advances in our understanding of the relationships between adipokines,
inflammation and the immune response have been achieved in the past 10 years. White …

TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine

A Maheshwari, DR Kelly, T Nicola, N Ambalavanan… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Premature neonates are predisposed to necrotizing enterocolitis
(NEC), an idiopathic, inflammatory bowel necrosis. We investigated whether NEC occurs in …

[HTML][HTML] Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine

RB McILwain, JG Timpa, AR Kurundkar, DW Holt… - Laboratory …, 2010 - Elsevier
Extracorporeal membrane oxygenation (ECMO) is a life-saving support system used in
neonates and young children with severe cardiorespiratory failure. Although ECMO has …

Circulating levels of chemerin and adiponectin are higher in ulcerative colitis and chemerin is elevated in Crohn's disease

J Weigert, F Obermeier, M Neumeier… - Inflammatory bowel …, 2010 - academic.oup.com
Background Chemerin is an adipokine that stimulates chemotaxis of cells of the innate
immune system. Inflammatory bowel disease (IBD) is linked to an impaired immune …

The role of chemerin in metabolic and cardiovascular disease: a literature review of its physiology and pathology from a nutritional perspective

L Tan, X Lu, AHJ Danser, K Verdonk - Nutrients, 2023 - mdpi.com
Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …

[HTML][HTML] Chemerin regulation and role in host defense

BA Zabel, M Kwitniewski, M Banas… - American journal of …, 2014 - ncbi.nlm.nih.gov
Chemerin is a widely distributed multifunctional secreted protein implicated in immune cell
migration, adipogenesis, osteoblastogenesis, angiogenesis, myogenesis, and glucose …

More than an adipokine: the complex roles of chemerin signaling in cancer

KB Goralski, AE Jackson, BT McKeown… - International journal of …, 2019 - mdpi.com
Chemerin is widely recognized as an adipokine, with diverse biological roles in cellular
differentiation and metabolism, as well as a leukocyte chemoattractant. Research …

Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytes

J Conde, R Gomez, G Bianco, M Scotece… - Annals of the …, 2011 - ard.bmj.com
Background Obesity is a major risk factor for a plethora of diseases including joint disorders
associated with cartilage destruction. Recently, it has been demonstrated that adipose tissue …

Effect of the microbiome on intestinal innate immune development in early life and the potential strategy of early intervention

Z Yang, X Liu, Y Wu, J Peng, H Wei - Frontiers in Immunology, 2022 - frontiersin.org
Early life is a vital period for mammals to be colonized with the microbiome, which
profoundly influences the development of the intestinal immune function. For neonates to …