The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …

Liver metastasis is the commonest form of distant metastasis in colorectal cancer. Selection
criteria for surgery and liver-directed therapies have recently been extended. However …

Colorectal cancer (CRC) is one of the most common cancers in the world. About two third of
patients with CRC will develop distant recurrence at some point in time. Liver is the most …

Colorectal cancer (CRC) is the third most common malignancy worldwide, with
approximately 50% of patients developing colorectal cancer liver metastasis (CRLM) during …

Background: Despite the recent worldwide dissemination of laparoscopic liver surgery, no
high-level evidence supports the oncologic safety of this approach. Objective: To evaluate …

Background Hepatic resection is considered the optimal potentially curative treatment for
colorectal liver metastases (CRLM). Following resection, up to two-thirds of patients will …

Simple Summary Patients with liver metastases can be scheduled for different therapies (eg,
chemotherapy, surgery, radiotherapy, and ablation). The choice of the most appropriate …

Purpose: Somatic gene mutations have been increasingly recognized to impact prognosis
following resection of colorectal liver metastases (CLM). We aimed to determine the impact …

PURPOSE To assess the effects of bevacizumab plus modified fluorouracil, leucovorin, and
oxaliplatin (mFOLFOX6) as first-line treatment of RAS mutant unresectable colorectal liver …

With a recent randomized prospective trial revealing that thermal ablative therapy as local
tumor control improved overall survival (OS) in patients with unresectable colorectal cancer …