The cyclopentenone unit is a very powerful synthon for the synthesis of a variety of bioactive
target molecules. This is due to the broad diversity of chemical modifications available for …

For many years, colchicine has been used for therapeutic purposes and has been given
considerable attention because of its association with tubulin and inhibition of small tubular …

Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease and is usually diagnosed in childhood, especially in the first decade of life …

The tropolone-bearing sesquiterpenes juniperone A (1) and norjuniperone A (2) were
isolated from the folk medicinal plant Juniperus chinensis, and their structures were …

Compounds that disrupt microtubule dynamics, such as colchicine, paclitaxel, or Vinca
alkaloids, have been broadly used in biological studies and have found application in …

This research descibes a pioneering approach aimed at preparing zinc oxide nanoparticles
(ZnO-NPs) with colchicine as the reducing and capping agent. Colchicine-loaded ZnO-NPs …

秋水仙碱是一种强效生物碱, 因其具有特殊的结构及药效, 受到人们广泛的关注.
多项研究都表明秋水仙碱体内血药浓度较低, 因此对其检测分析方法的灵敏度要求较高 …

The photolysis of colchicine under ultraviolet and visible light irradiation was studied by
ultraviolet (UV) scanning and HPLC-MS. The photoproduct was proposed and the …

Colchicine is an active pharmaceutical ingredient widely used for treating gout, pericarditis,
and familial Mediterranean fever with high antimitotic activity. The photoisomerization of …

Abstract The furo [2, 3-b] pyridine moiety is an important scaffold for many biologically active
compounds, therefore, the spectral data of the derivative 1-(3-Amino-6-(2, 5 …