Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
degeneration of motor neurons in the brain and spinal cord. The causes of ALS are not fully …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder and the most common
motor neuron disease. ALS shows substantial clinical and molecular heterogeneity. In vitro …

Amyotrophic lateral sclerosis (ALS) is manifested as skeletal muscle denervation, loss of
motor neurons and finally severe respiratory failure. Mutations of RNA-binding protein FUS …

Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic
heterogeneity. Machine learning approaches have previously been utilised for patient …

Amyotrophic lateral sclerosis (ALS) is an incurable disease characterized by proteinaceous
aggregate accumulation and neuroinflammation culminating in rapidly progressive lower …

Elevating neuroprotective proteins using adeno-associated virus (AAV)-mediated gene
delivery shows great promise in combating devastating neurodegenerative diseases …

Alzheimer's disease (AD) is the most common form of neurodegeneration and cognitive
dysfunction in the elderly. Identifying molecular signals that mitigate and reverse …

Objective Neurofilament heavy‐chain gene (NEFH) variants are associated with multiple
neurodegenerative diseases, however, their relationship with ALS has not been robustly …

Background Amyotrophic lateral sclerosis (ALS) displays considerable clinical, genetic and
molecular heterogeneity. Machine learning approaches have shown potential to disentangle …

The majority of amyotrophic lateral sclerosis (ALS) is caused by a complex gene-
environment interaction. Despite high estimates of heritability, the genetic basis of disease in …