The use of cell models is common to mimic cellular and molecular events in interaction with
their environment. In the case of the gut, the existing models are of particular interest to …

Organoid models have revolutionized cancer research through their ability to capture the
cellular heterogeneity and spatial organization of a tumor in 3D culture. Patient-derived …

After birth, animals are colonized by a diverse community of microorganisms. The digestive
tract is known to contain the largest number of microbiome in the body. With emergence of …

Methods and Results Colonic organoids were co-cultured with human embryonic stem cell
(hESC)-derived peripheral neurons, resulting in the morphological maturation of columnar …

Purpose Recently, interest is increasing in using prebiotics, which are nutrient ingredients of
live microorganism that improve the intestinal environments by promoting the growth of …

Model organisms have played essential roles in biological studies over the centuries.
Typically fast-growing in laboratory settings and fertile with numerous offsprings, various …

Patients with coronavirus disease 2019 (COVID-19), which has recently caused a pandemic,
have reported symptoms of coronavirus infection that are not well understood by the medical …

L'épithélium intestinal et le microbiote intestinal sont en équilibre dans l'intestin. Cependant,
cet équilibre peut être rompu par différents facteurs endogènes ou exogènes, conduisant à …