Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Purely covalent molecular cages and containers for guest encapsulation

G Montà-González, F Sancenón… - Chemical …, 2022 - ACS Publications
Cage compounds offer unique binding pockets similar to enzyme-binding sites, which can
be customized in terms of size, shape, and functional groups to point toward the cavity and …

Molecular boronic acid-based saccharide sensors

GT Williams, JL Kedge, JS Fossey - ACS sensors, 2021 - ACS Publications
Boronic acids can reversibly bind diols, a molecular feature that is ubiquitous within
saccharides, leading to their use in the design and implementation of sensors for numerous …

Rational design of mesoporous chiral MOFs as reactive pockets in nanochannels for enzyme-free identification of monosaccharide enantiomers

J Guo, X Liu, J Zhao, H Xu, Z Gao, ZQ Wu… - Chemical Science, 2023 - pubs.rsc.org
Monosaccharides play significant roles in daily metabolism in living organisms. Although
various devices have been constructed for monosaccharide identification, most rely on the …

Circular dichroism based chirality sensing with supramolecular host–guest chemistry

M Quan, XY Pang, W Jiang - Angewandte Chemie, 2022 - Wiley Online Library
Optical methods are promising to address the ever‐increasing demands for chirality analysis
in drug discovery and related fields because they are amenable to high‐throughput …

'Smart'insulin-delivery technologies and intrinsic glucose-responsive insulin analogues

MA Jarosinski, B Dhayalan, N Rege, D Chatterjee… - Diabetologia, 2021 - Springer
Insulin replacement therapy for diabetes mellitus seeks to minimise excursions in blood
glucose concentration above or below the therapeutic range (hyper-or hypoglycaemia). To …

Molecular cages for biological applications

L Tapia, I Alfonso, J Solà - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
Artificial receptors able to recognise biologically relevant molecules or ions have gained
interest in the chemical community because they offer a plethora of posibilities. Molecular …

Pd nanocatalysts adsorbed onto silica nanoparticle coated indium tin oxide: a reusable nanozyme for glucose detection

R Chavalala, P Mashazi - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Nanozymes are nanomaterials that exhibit enzyme-like activity upon exposure to a substrate
solution. The use of noble and platinum group metals enhances enzyme-like catalytic …

A Green and Wide‐Scope Approach for Chiroptical Sensing of Organic Molecules through Biomimetic Recognition in Water

LL Wang, M Quan, TL Yang, Z Chen… - Angewandte …, 2020 - Wiley Online Library
Optical chirality sensing has attracted a lot of interest due to its potential in high‐throughput
screening in chirality analysis. A molecular sensor is required to convert the chirality of …

Switchable bifunctional molecular recognition in water using a pH-responsive Endo-functionalized cavity

X Wang, M Quan, H Yao, XY Pang, H Ke… - Nature …, 2022 - nature.com
The construction of water-soluble synthetic hosts with a stimuli-responsive endo-
functionalized cavity is challenging. These hosts feature a switchable cavity and may bring …