Although the generation of movements is a fundamental function of the nervous system, the
underlying neural principles remain unclear. As flexor and extensor muscle activities …

CLARITY is a tissue clearing method, which enables immunostaining and imaging of large
volumes for 3D-reconstruction. The method was initially time-consuming, expensive and …

Understanding the pathophysiological changes triggered by an acute spinal cord injury is a
primary goal to prevent and treat chronic disability with a mechanism-based approach. After …

Neural processing in the brain controls behavior through descending neurons (DNs)-
neurons which carry signals from the brain to the spinal cord (or thoracic ganglia in insects) …

The cellular composition of brains shows largely conserved, gradual evolutionary trends
between species. In the primate spinal cord, however, the glia–neuron ratio was reported to …

When spinal circuits generate rhythmic movements it is important that the neuronal activity
remains within stable bounds to avoid saturation and to preserve responsiveness. Here, we …

Modular organization of the spinal motor system is thought to reduce the cognitive
complexity of simultaneously controlling the large number of muscles and joints in the …

Direct measurements of synaptic inhibition (I) and excitation (E) to spinal motoneurons can
provide an important insight into the organization of premotor networks. Such measurements …

During the generation of rhythmic movements, most spinal neurons receive an oscillatory
synaptic drive. The neuronal architecture underlying this drive is unknown, and the …

Background In this work, we propose to catch the complexity of the membrane potential's
dynamic of a motoneuron between its spikes, taking into account the spikes from other …