Role of the microbiome in human development

MG Dominguez-Bello, F Godoy-Vitorino, R Knight… - Gut, 2019 - gut.bmj.com
The host-microbiome supraorganism appears to have coevolved and the unperturbed
microbial component of the dyad renders host health sustainable. This coevolution has likely …

Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis

M Pammi, J Cope, PI Tarr, BB Warner, AL Morrow… - Microbiome, 2017 - Springer
Background Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and
microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the …

Clinical implications of preterm infant gut microbiome development

DB Healy, CA Ryan, RP Ross, C Stanton… - Nature …, 2022 - nature.com
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

Factors affecting gastrointestinal microbiome development in neonates

CYL Chong, FH Bloomfield, JM O'Sullivan - Nutrients, 2018 - mdpi.com
The gut microbiome is established in the newborn period and is recognised to interact with
the host to influence metabolism. Different environmental factors that are encountered …

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

HS Deshmukh, Y Liu, OR Menkiti, J Mei, N Dai… - Nature medicine, 2014 - nature.com
Neonatal colonization by microbes, which begins immediately after birth, is influenced by
gestational age and the mother's microbiota and is modified by exposure to antibiotics. In …

Development of intestinal microbiota in infants and its impact on health

S Matamoros, C Gras-Leguen, F Le Vacon, G Potel… - Trends in …, 2013 - cell.com
Throughout the human lifetime, the intestinal microbiota performs vital functions, such as
barrier function, metabolic reactions, trophic effects, and maturation of the host's innate and …

Necrotizing enterocolitis

J Neu, WA Walker - New England Journal of Medicine, 2011 - Mass Medical Soc
Necrotizing Enterocolitis | New England Journal of Medicine Skip to main content Access
provided byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine …

High-throughput sequencing reveals the incomplete, short-term recovery of infant gut microbiota following parenteral antibiotic treatment with ampicillin and …

F Fouhy, CM Guinane, S Hussey, R Wall… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The infant gut microbiota undergoes dramatic changes during the first 2 years of life. The
acquisition and development of this population can be influenced by numerous factors, and …

Development of the human infant intestinal microbiota

C Palmer, EM Bik, DB DiGiulio, DA Relman… - PLoS …, 2007 - journals.plos.org
Almost immediately after a human being is born, so too is a new microbial ecosystem, one
that resides in that person's gastrointestinal tract. Although it is a universal and integral part …

Prolonged initial empirical antibiotic treatment is associated with adverse outcomes in premature infants

VS Kuppala, J Meinzen-Derr, AL Morrow… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To investigate the outcomes after prolonged empirical antibiotic administration
to premature infants in the first week of life, and concluding subsequent late onset sepsis …