Obtaining genetics insights from deep learning via explainable artificial intelligence

G Novakovsky, N Dexter, MW Libbrecht… - Nature Reviews …, 2023 - nature.com
Artificial intelligence (AI) models based on deep learning now represent the state of the art
for making functional predictions in genomics research. However, the underlying basis on …

Deep learning modelling techniques: current progress, applications, advantages, and challenges

SF Ahmed, MSB Alam, M Hassan, MR Rozbu… - Artificial Intelligence …, 2023 - Springer
Deep learning (DL) is revolutionizing evidence-based decision-making techniques that can
be applied across various sectors. Specifically, it possesses the ability to utilize two or more …

Machine learning in drug discovery: a review

S Dara, S Dhamercherla, SS Jadav, CHM Babu… - Artificial intelligence …, 2022 - Springer
This review provides the feasible literature on drug discovery through ML tools and
techniques that are enforced in every phase of drug development to accelerate the research …

An introductory review of deep learning for prediction models with big data

F Emmert-Streib, Z Yang, H Feng, S Tripathi… - Frontiers in Artificial …, 2020 - frontiersin.org
Deep learning models stand for a new learning paradigm in artificial intelligence (AI) and
machine learning. Recent breakthrough results in image analysis and speech recognition …

CRISPR–Cas9 gRNA efficiency prediction: an overview of predictive tools and the role of deep learning

V Konstantakos, A Nentidis, A Krithara… - Nucleic Acids …, 2022 - academic.oup.com
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated
protein 9 (Cas9) system has become a successful and promising technology for gene …

Applications of machine learning in drug discovery and development

J Vamathevan, D Clark, P Czodrowski… - Nature reviews Drug …, 2019 - nature.com
Drug discovery and development pipelines are long, complex and depend on numerous
factors. Machine learning (ML) approaches provide a set of tools that can improve discovery …

Machine learning in materials science

J Wei, X Chu, XY Sun, K Xu, HX Deng, J Chen, Z Wei… - InfoMat, 2019 - Wiley Online Library
Traditional methods of discovering new materials, such as the empirical trial and error
method and the density functional theory (DFT)‐based method, are unable to keep pace …

Deep learning and artificial intelligence methods for Raman and surface-enhanced Raman scattering

F Lussier, V Thibault, B Charron, GQ Wallace… - TrAC Trends in …, 2020 - Elsevier
Abstract Machine learning is shaping up our lives in many ways. In analytical sciences,
machine learning provides an unprecedented opportunity to extract information from …

Review of big data analytics, artificial intelligence and nature-inspired computing models towards accurate detection of COVID-19 pandemic cases and contact tracing

IE Agbehadji, BO Awuzie, AB Ngowi… - International journal of …, 2020 - mdpi.com
The emergence of the 2019 novel coronavirus (COVID-19) which was declared a pandemic
has spread to 210 countries worldwide. It has had a significant impact on health systems …

Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions

S Vatansever, A Schlessinger, D Wacker… - Medicinal research …, 2021 - Wiley Online Library
Neurological disorders significantly outnumber diseases in other therapeutic areas.
However, developing drugs for central nervous system (CNS) disorders remains the most …