Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Nanoparticles: Taking a unique position in medicine

TM Joseph, D Kar Mahapatra, A Esmaeili, Ł Piszczyk… - Nanomaterials, 2023 - mdpi.com
The human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In
parallel with our history of civilization, interest in scientific approaches to unravel …

[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

MF Attia, N Anton, J Wallyn, Z Omran… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives This review highlights both the physicochemical characteristics of the
nanocarriers (NCs) and the physiological features of tumour microenvironment (TME) to …

Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

F Farjadian, A Ghasemi, O Gohari, A Roointan… - …, 2019 - Taylor & Francis
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up

MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …

Toxicity of metal-based nanoparticles: Challenges in the nano era

N Zhang, G Xiong, Z Liu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
With the rapid progress of nanotechnology, various nanoparticles (NPs) have been
applicated in our daily life. In the field of nanotechnology, metal-based NPs are an important …

[HTML][HTML] Intranasal delivery of nanostructured lipid carriers, solid lipid nanoparticles and nanoemulsions: A current overview of in vivo studies

CP Costa, JN Moreira, JMS Lobo, AC Silva - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The management of the central nervous system (CNS) disorders is challenging, due to the
need of drugs to cross the blood‒brain barrier (BBB) and reach the brain. Among the …