Advances in mapping tumor progression from precancer atlases

Z Chen, KS Lau - Cancer Prevention Research, 2023 - AACR
Tissue profiling technologies present opportunities for understanding transition from
precancerous lesions to malignancy, which may impact risk stratification, prevention, and …

Extended correlation functions for spatial analysis of multiplex imaging data

JA Bull, EJ Mulholland, SJ Leedham, HM Byrne - Biological Imaging, 2024 - cambridge.org
Imaging platforms for generating highly multiplexed histological images are being
continually developed and improved. Significant improvements have also been made in the …

The influence of resolution on the predictive power of spatial heterogeneity measures as biomarkers of liver fibrosis

J Claes, A Agten, A Blázquez-Moreno, M Crabbe… - Computers in Biology …, 2024 - Elsevier
Spatial heterogeneity of cells in liver biopsies can be used as biomarker for disease severity
of patients. This heterogeneity can be quantified by non-parametric statistics of point pattern …

SpatialQPFs: An R package for deciphering cell-cell spatial relationship

X Li - bioRxiv, 2024 - biorxiv.org
Understanding the spatial dynamics within tissue microenvironments is crucial for
deciphering cellular interactions and molecular signaling in living systems. These spatial …

[HTML][HTML] Self-supervised deep learning for highly efficient spatial immunophenotyping

H Zhang, K AbdulJabbar, T Grunewald, AU Akarca… - …, 2023 - thelancet.com
Background Efficient biomarker discovery and clinical translation depend on the fast and
accurate analytical output from crucial technologies such as multiplex imaging. However …