Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The 70-kDa heat shock protein (HSP70) family of molecular chaperones represents one of
the most ubiquitous classes of chaperones and is highly conserved in all organisms …

Rationale: Mitochondria are semiautonomous cellular organelles with their own genome,
which not only supply energy but also participate in cell death pathways. MicroRNAs …

Abstract MicroRNA-21 (miR-21) is a highly expressed microRNA (miRNA) in cardiovascular
system. Recent studies have revealed that its expression is deregulated in heart and …

Heat shock proteins (HSP) are a subset of the molecular chaperones, best known for their
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …

MicroRNA-21 (miR-21) is highly up-regulated during hypertrophic and cancerous cell
growth. In contrast, we found that it declines in cardiac myocytes upon exposure to hypoxia …

Aims The aims of the present study are to determine the miRNA expression signature in rat
hearts after ischaemic preconditioning (IP) and to identify an IP-regulated miRNA, miR-21, in …

The miR-15/107 group of microRNA (miRNA) gene is increasingly appreciated to serve key
functions in humans. These miRNAs regulate gene expression involved in cell division …