Tendon disorders are common and lead to significant disability, pain, healthcare cost, and
lost productivity. A wide range of injury mechanisms exist leading to tendinopathy or tendon …

Biomaterial scaffolds have been extensively used to deliver growth factors to induce new
bone formation. The pharmacokinetics of growth factor delivery has been a critical regulator …

Purpose The purpose of this study was to evaluate the efficiency of biologic augmentation of
rotator cuff repair with iliac crest bone marrow-derived mesenchymal stem cells (MSCs). The …

Despite advances in surgical reconstruction of chronic rotator cuff (RC) tears leading to
improved clinical outcomes, failure rates of 13–94% have been reported. Reasons for this …

Background: Arthroscopic rotator cuff repair has a high rate of patient satisfaction. However,
multiple studies have shown significant rates of anatomic failure. Biological augmentation …

The 4 fibrocartilagenous transition zones of the rotator cuff insertion site are not recreated
following surgical repair. Instead, a layer of scar tissue is formed between the tendon and …

Abstract On May 22, 2017, the National Institutes of Health (NIH)/National Institute of Arthritis
and Musculoskeletal and Skin Diseases (NIAMS) hosted a roundtable on “Innovative …

Augmentation of Tendon-to-Bone Healing : JBJS Augmentation of Tendon-to-Bone Healing :
JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques Open Access JOPA …

Strategies in Biologic Augmentation of Rotator Cuff Repair:... : Clinical Orthopaedics and Related
Research® Strategies in Biologic Augmentation of Rotator Cuff Repair: A Review : Clinical …

Background Rotator cuff tears are a common source of shoulder pain. High rates (20%-94%)
of structural failure of the repair have been attributed to multiple factors, including poor repair …