Fucose is a 6-deoxy hexose in the l-configuration found in a large variety of different
organisms. In mammals, fucose is incorporated into N-glycans, O-glycans and glycolipids by …

Fucosylation is a biological process broadly observed in vertebrates, invertebrates, plants,
bacteria, and fungi. Fucose moieties on cell-surface glycans are increasingly recognized as …

Glycosylation produces a diverse and abundant repertoire of glycans, which are collectively
known as the glycome. Glycans are one of the four fundamental macromolecular …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade proteins of the
extracellular matrix and the basement membrane. Thus, these enzymes regulate airway …

Several studies have implicated a causative role for specific matrix metalloproteinases
(MMPs) in the development and progression of cigarette smoke-induced chronic obstructive …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality
globally and the risk of developing lung cancer is six times greater in individuals with COPD …

A code is defined by the nature of the symbols, which are used to generate information‐
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …

Cells undergo proliferation and apoptosis, migration and differentiation via a number of cell
surface receptors, most of which are heavily glycosylated. This review discusses receptor …

Background Body traits are generally controlled by several genes in vertebrates (ie
polygenes), which in turn make them difficult to identify through association mapping …

The cytoplasmic peptide: N-glycanase (Ngly1 in mammals) is a de-N-glycosylating enzyme
that is highly conserved among eukaryotes. It was recently reported that subjects harboring …