Recent approaches for downplaying antibiotic resistance: molecular mechanisms

S Ahmed, MZ Ahmed, S Rafique… - BioMed Research …, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is a ubiquitous public health menace. AMR emergence
causes complications in treating infections contributing to an upsurge in the mortality rate …

Vaccines and monoclonal antibodies to prevent healthcare-associated bacterial infections

L Sauvat, PO Verhoeven, J Gagnaire… - Clinical Microbiology …, 2024 - journals.asm.org
Healthcare-associated infections (HAIs) represent a burden for public health with a high
prevalence and high death rates associated with them. Pathogens with a high potential for …

Comparative analysis of phyto-fabricated chitosan, copper oxide, and chitosan-based CuO nanoparticles: antibacterial potential against Acinetobacter baumannii …

MH Sarfraz, M Zubair, B Aslam, A Ashraf… - Frontiers in …, 2023 - frontiersin.org
The aim of this study was to provide a comparative analysis of chitosan (CH), copper oxide
(CuO), and chitosan-based copper oxide (CH-CuO) nanoparticles for their application in the …

Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach

S Gul, S Ahmad, A Ullah, S Ismail, M Khurram… - Vaccines, 2022 - mdpi.com
Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …

Biomimetic Neutrophil Nanotoxoids Elicit Potent Immunity against Acinetobacter baumannii in Multiple Models of Infection

J Zhou, CJ Ventura, Y Yu, W Gao, RH Fang… - Nano letters, 2022 - ACS Publications
Acinetobacter baumannii is a leading cause of antibiotic-resistant nosocomial infections with
high mortality rates, yet there is currently no clinically approved vaccine formulation. During …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Hit 'em Where It Hurts: Gram-Negative Bacterial Lipopolysaccharide as a Vaccine Target

AS Cross - Microbiology and Molecular Biology Reviews, 2023 - Am Soc Microbiol
Infections with antimicrobial-resistant (AMR) bacteria pose an increasing threat to the ability
to perform surgical procedures, organ transplantation, and treat cancer among many other …

Stereoselective Synthesis of the O‐antigen of A. baumannii ATCC 17961 Using Long‐Range Levulinoyl Group Participation

L Duan, Q Nie, Y Hu, L Wang, K Guo… - Angewandte …, 2023 - Wiley Online Library
Herein, we described the first synthesis of the pentasaccharide and decasaccharide of the A.
baumannii ATCC 17961 O‐antigen for developing a synthetic carbohydrate‐based vaccine …

Chemical Synthesis and Antigenic Evaluation of Inner Core Oligosaccharides from Acinetobacter baumannii Lipopolysaccharide

XY Zhou, LX Li, Z Zhang, SC Duan… - Angewandte Chemie …, 2022 - Wiley Online Library
Acinetobacter baumannii is currently posing a serious threat to global health.
Lipopolysaccharide (LPS) is a potent virulence factor of pathogenic Gram‐negative bacteria …

Acinetobacter baumannii: assessing susceptibility patterns, management practices, and mortality predictors in a tertiary teaching hospital in Lebanon

R Itani, HMJ Khojah, S Karout, D Rahme… - … Resistance & Infection …, 2023 - Springer
Background Acinetobacter baumannii is a major nosocomial pathogen capable of causing
life-threatening infections. This bacterium is highly resistant to antibiotics and associated …