Enantioselective radical reactions using chiral catalysts

S Mondal, F Dumur, D Gigmes, MP Sibi… - Chemical …, 2022 - ACS Publications
Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

Transition metal catalysis controlled by hydrogen bonding in the second coordination sphere

JNH Reek, B de Bruin, S Pullen, TJ Mooibroek… - Chemical …, 2022 - ACS Publications
Transition metal catalysis is of utmost importance for the development of sustainable
processes in academia and industry. The activity and selectivity of metal complexes are …

Strategies and Mechanisms of First-Row Transition Metal-Regulated Radical C–H Functionalization

X Wang, J He, YN Wang, Z Zhao, K Jiang… - Chemical …, 2024 - ACS Publications
Radical C–H functionalization represents a useful means of streamlining synthetic routes by
avoiding substrate preactivation and allowing access to target molecules in fewer steps. The …

Metal-Catalyzed Enantioconvergent Transformations

M Yus, C Nájera, F Foubelo, JM Sansano - Chemical Reviews, 2023 - ACS Publications
Enantioconvergent catalysis has expanded asymmetric synthesis to new methodologies
able to convert racemic compounds into a single enantiomer. This review covers recent …

Nitrene transfer catalysts for enantioselective C–N bond formation

M Ju, JM Schomaker - Nature Reviews Chemistry, 2021 - nature.com
Abstract Transition-metal-catalysed, non-enzymatic transformations of C–H and C= C bonds
to C–N bonds through nitrene transfer (NT) are powerful synthetic tools to prepare valuable …

Highly regio-and enantioselective reductive coupling of alkynes and aldehydes via photoredox cobalt dual catalysis

YL Li, SQ Zhang, J Chen, JB Xia - Journal of the American …, 2021 - ACS Publications
A Co-catalyzed highly regio-and enantioselective reductive coupling of alkynes and
aldehydes has been developed under visible light photoredox dual catalysis. A variety of …

A Counterion/Ligand-Tuned Chemo-and Enantioselective Copper-Catalyzed Intermolecular Radical 1, 2-Carboamination of Alkenes

XY Cheng, YF Zhang, JH Wang, QS Gu… - Journal of the …, 2022 - ACS Publications
The copper-catalyzed enantioselective intermolecular radical 1, 2-carboamination of
alkenes with readily accessible alkyl halides is an appealing strategy for producing chiral …

Synthesis of α‐Quaternary β‐Lactams via Copper‐Catalyzed Enantioconvergent Radical C(sp3)−C(sp2) Cross‐Coupling with Organoboronate Esters

FL Wang, L Liu, CJ Yang, C Luan… - Angewandte Chemie …, 2023 - Wiley Online Library
The copper‐catalyzed enantioconvergent radical C (sp3)− C (sp2) cross‐coupling of tertiary
α‐bromo‐β‐lactams with organoboronate esters could provide the synthetically valuable α …

Regio-and Enantioselective Catalytic δ-C–H Amidation of Dioxazolones Enabled by Open-Shell Copper-Nitrenoid Transfer

S Kim, SL Song, J Zhang, D Kim, S Hong… - Journal of the …, 2023 - ACS Publications
Controlling regio-and enantioselectivity in C–H functionalization reactions is of paramount
importance due to their versatile synthetic utilities. Herein, we describe a new approach for …

Metalloradical Catalysis: General Approach for Controlling Reactivity and Selectivity of Homolytic Radical Reactions

WCC Lee, XP Zhang - Angewandte Chemie International …, 2024 - Wiley Online Library
Since Friedrich Wöhler's groundbreaking synthesis of urea in 1828, organic synthesis over
the past two centuries has predominantly relied on the exploration and utilization of …