A review on natural biopolymers in external drug delivery systems for wound healing and atopic dermatitis

PC Pires, F Damiri, EN Zare, A Hasan… - International Journal of …, 2024 - Elsevier
Despite the advantages of topical administration in the treatment of skin diseases, current
marketed preparations face the challenge of the skin's barrier effect, leading to low …

A transdermal drug delivery system based on nucleic acid nanomaterials for skin photodamage treatment

Y Xie, J He, S Li, X Chen, T Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Skin photodamage, which is induced by ultraviolet (UV) radiation, is a prevalent cause of
skin damage. In this study, a transdermal drug delivery system is developed for the topical …

Novel therapeutic hybrid systems using hydrogels and nanotechnology: a focus on nanoemulgels for the treatment of skin diseases

K Sghier, M Mur, F Veiga, AC Paiva-Santos, PC Pires - Gels, 2024 - mdpi.com
Topical and transdermal drug delivery are advantageous administration routes, especially
when treating diseases and conditions with a skin etiology. Nevertheless, conventional …

Dimethyl Fumarate-Loaded Transethosomes: A Formulative Study and Preliminary Ex Vivo and In Vivo Evaluation

F Ferrara, M Benedusi, F Cervellati… - International Journal of …, 2022 - mdpi.com
In this study, transethosomes were investigated as potential delivery systems for dimethyl
fumarate. A formulative study was performed investigating the effect of the composition of …

[HTML][HTML] pH-sensitive in situ gel of mirtazapine Invasomes for rectal drug delivery: Protruded bioavailability and anti-depressant efficacy

EM Eissa, AM El Sisi, MA Bekhet, FIA El-Ela… - Pharmaceuticals, 2024 - mdpi.com
The present research emphasizes fabrication alongside the assessment of an innovative
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …

Vesicular nanocarriers for phytocompounds in wound care: preparation and characterization

DA Safta, C Bogdan, ML Moldovan - Pharmaceutics, 2022 - mdpi.com
The need to develop wound healing preparations is a pressing challenge given the
limitations of the current treatment and the rising prevalence of impaired healing wounds …

Erythromycin formulations—a journey to advanced drug delivery

VM Platon, B Dragoi, L Marin - Pharmaceutics, 2022 - mdpi.com
Erythromycin (ERY) is a macrolide compound with a broad antimicrobial spectrum which is
currently being used to treat a large number of bacterial infections affecting the skin …

Phytosterol-mediated glycerosomes combined with peppermint oil enhance transdermal delivery of lappaconitine by modulating the lipid composition of the stratum …

H Ruan, L Shen, X Hou, J Li, T Guo, C Zhu… - Drug Delivery and …, 2023 - Springer
Although the introduction of glycerosomes has enriched strategies for efficient transdermal
drug delivery, the inclusion of cholesterol as a membrane stabilizer has limited their clinical …

The evolution of emerging nanovesicle technologies for enhanced delivery of molecules into and across the skin

E Touitou, H Natsheh - Pharmaceutics, 2024 - mdpi.com
This review focuses on nanovesicular carriers for enhanced delivery of molecules into and
across the skin, from their design to recent emerging technologies. During the last four …

Nano-vesicular systems for melanocytes targeting and melasma treatment: In-vitro characterization, ex-vivo skin retention, and preliminary clinical appraisal

S Hatem, AO Kamel, SA Elkheshen, M Nasr… - International Journal of …, 2024 - Elsevier
Melasma represents an acquired melanogenesis disorder resulting in skin's
hyperpigmentation effect. Although several approaches are adopted for melasma treatment …