Application of proteomics in cancer: recent trends and approaches for biomarkers discovery

YW Kwon, HS Jo, S Bae, Y Seo, P Song, M Song… - Frontiers in …, 2021 - frontiersin.org
Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …

Adipokines, myokines, and hepatokines: crosstalk and metabolic repercussions

AR de Oliveira dos Santos… - International Journal of …, 2021 - mdpi.com
Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Secretome of stromal cancer-associated fibroblasts (CAFs): Relevance in cancer

D Mishra, D Banerjee - Cells, 2023 - mdpi.com
The cancer secretome reflects the assortment of proteins released by cancer cells.
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …

High-throughput assays to assess variant effects on disease

K Ma, LO Gauthier, F Cheung… - Disease Models & …, 2024 - journals.biologists.com
Interpreting the wealth of rare genetic variants discovered in population-scale sequencing
efforts and deciphering their associations with human health and disease present a critical …

Astrocyte–oligodendrocyte–microglia crosstalk in astrocytopathies

DM de Waard, M Bugiani - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Defective astrocyte function due to a genetic mutation can have major consequences for
microglia and oligodendrocyte physiology, which in turn affects the white matter integrity of …

[HTML][HTML] Proteomics and its applications in breast cancer

AN Neagu, D Whitham, E Buonanno… - American journal of …, 2021 - ncbi.nlm.nih.gov
Breast cancer is an individually unique, multi-faceted and chameleonic disease, an eternal
challenge for the new era of high-integrated precision diagnostic and personalized …

Adipose-derived stem cell secretome as a cell-free product for cutaneous wound healing

A Ajit, I Ambika Gopalankutty - 3 Biotech, 2021 - Springer
Chronic wounds continue to be a substantial public health concern contributing to both
humanistic and economic burden worldwide. The magnitude of chronic wounds as a global …

[HTML][HTML] Comparative proteomics and secretomics revealed virulence, and coresistance-related factors in non O1/O139 Vibrio cholerae recovered from 16 species of …

X Shan, J Fu, X Li, X Peng, L Chen - Journal of Proteomics, 2022 - Elsevier
Vibrio cholerae can cause pandemic cholera in humans. The bacterium resides in aquatic
environments worldwide. Identification of risk factors of V. cholerae in aquatic products is …

In vitro skeletal muscle models for type 2 diabetes

CY Sheng, YH Son, J Jang, SJ Park - Biophysics Reviews, 2022 - pubs.aip.org
Type 2 diabetes mellitus, a metabolic disorder characterized by abnormally elevated blood
sugar, poses a growing social, economic, and medical burden worldwide. The skeletal …

Trypanosoma evansi secretome carries potential biomarkers for Surra diagnosis

RS Moreira, NA Calomeno, GB das Neves… - Journal of …, 2023 - Elsevier
Trypanosoma evansi is a parasite that is phylogenetically close to Trypanosoma brucei and
is the causative agent of a disease known as surra. Surra is responsible for a high mortality …