Altered pathways and targeted therapy in double hit lymphoma

Y Zhuang, J Che, M Wu, Y Guo, Y Xu, X Dong… - Journal of Hematology & …, 2022 - Springer
High-grade B-cell lymphoma with translocations involving MYC and BCL2 or BCL6, usually
referred to as double hit lymphoma (DHL), is an aggressive hematological malignance with …

R-CHOP Vs DA-EPOCH-R for double-expressor lymphoma: a University of California hematologic malignancies consortium retrospective analysis

T Othman, J Penaloza, S Zhang, CE Daniel… - … Myeloma and Leukemia, 2022 - Elsevier
Background Managing double-expressor lymphomas (DEL) is controversial given the dearth
of data and lack of standardized guidelines on this high-risk subset of lymphomas. No …

Zanubrutinib plus R‐CHOP for the treatment of newly diagnosed double‐expressor lymphoma: A phase 2 clinical study

X Yin, Q He, D Liu, L Xie, H Wang, C Chen, C Zhao… - Cancer, 2025 - Wiley Online Library
Background Double‐expressor lymphoma (DEL) has a poorer prognosis than other
subtypes of diffuse large B‐cell lymphoma (DLBCL). This study is a multicenter, prospective …

Do Double-Expressor High-Grade B-Cell Lymphomas Really Need Intensified Treatment? A Report from the Real-Life Series of High-Grade B-Cell Lymphomas …

L Boltežar, S Rožman, G Gašljević, B Grčar Kuzmanov… - Biomedicines, 2024 - mdpi.com
High-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements are known
for their aggressive clinical course and so are the ones with MYC and BCL2 protein …

DA-EPOCH-R improves the prognosis of patients with double-expressor lymphoma: A single-center retrospective study and meta-analysis

J Zhan, S Yang, W Zhang, D Zhou, Y Zhang, W Wang… - Medicine, 2022 - journals.lww.com
Purpose: Double-expressor lymphoma (DEL) is associated with a poor prognosis. The
standard treatment for patients with DEL remains controversial. A comparison of the safety …

Double‑hit primary lymphoma (MYC and BCL2) in the bilateral ovary: A case report

Y Zhang, W Wang, T Chen - Oncology Letters, 2023 - spandidos-publications.com
Abstract Lymphoid neoplasm with 18q21. 3/BCL2 and 8q24/MYC translocation to
immunoglobulin genes as dual‑hit lymphoma in female bilateral ovaries is rare and has a …

Unmet needs in the first-line treatment of diffuse large B-cell lymphoma: Expert recommendations from the Asia-Pacific region with a focus on the challenging subtypes

D Tan, JY Chan, K Wudhikarn, RSM Wong… - … Myeloma and Leukemia, 2024 - Elsevier
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin
lymphoma, accounting for around 30–60% of all cases. The management of DLBCL in Asia …

R-CHOP vs R-DA-EPOCH for Double-Expressor Lymphoma: A Meta-Analysis

R Wu, M Zhang, Y Liu, Y Liu, P Zhao - Blood&Genomics, 2024 - blood-genomics.com
Abstract Double-expressor lymphoma (DEL), a subtype of diffuse large B-cell lymphoma
(DLBCL), presents a poor prognosis. The traditional R-CHOP regimen has been ineffective …

[引用][C] Bone marrow involvement and risk of tuberculosis reactivation in adults with lymphoma

P Kanya, P Sirijanchune, W Imsanguan - The Clinical Academia, 2023