Recent developments in biomineralization have already demonstrated that nanosized
particles play an important role in the formation of hard tissues of animals. Namely, the basic …

Anticancer therapies and regenerative medicine are being developed to destroy tumor cells,
as well as remodel, replace, and support injured organs and tissues. Nowadays, a suitable …

Due to a great chemical similarity with the biological calcified tissues, many calcium
orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists …

Osteomyelitis is a progressive inflammatory disease requiring prolonged systemic treatment
with high antibiotic doses, and is very challenging to be treated. The use of locally applied …

Nano-sized particles and crystals play an important role in the formation of calcified tissues
of various animals. For example, nano-sized and nanocrystalline calcium orthophosphates …

Collagen hydrogel has been widely used for osteochondral repair, but its mechanical
properties cannot meet the requirements of clinical application. Previous studies have …

Abstract Nano-hydroxyapatite/poly (l-lactic acid)(nano-HA/PLLA) composites with uniform
HA distribution and good mechanical performance were fabricated by a modified in situ …

The objective of this study was to develop a collagen/hydroxyapatite (HA) nanocomposite
scaffold for bone tissue engineering applications. For this purpose, in situ mineralization of …

Nanometric particles and crystals play very important roles in biological systems. For
example, calcium orthophosphates (abbreviated as CaPO4) of nanometric dimensions …

High local intraosseous levels of antimicrobial agents are required for adequate long-term
treatment of chronic osteomyelitis (OM). In this study, biodegradable composite scaffolds of …