C–H activation

T Rogge, N Kaplaneris, N Chatani, J Kim… - Nature Reviews …, 2021 - nature.com
Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

Mn-, Fe-, and Co-catalyzed radical hydrofunctionalizations of olefins

SWM Crossley, C Obradors, RM Martinez… - Chemical …, 2016 - ACS Publications
Cofactor-mimetic aerobic oxidation has conceptually merged with catalysis of syngas
reactions to form a wide range of Markovnikov-selective olefin radical …

Photochemical approaches to complex chemotypes: applications in natural product synthesis

MD Karkas, JA Porco Jr, CRJ Stephenson - Chemical Reviews, 2016 - ACS Publications
The use of photochemical transformations is a powerful strategy that allows for the formation
of a high degree of molecular complexity from relatively simple building blocks in a single …

State-of-the-art biocatalysis

JB Pyser, S Chakrabarty, EO Romero… - ACS central …, 2021 - ACS Publications
The use of enzyme-mediated reactions has transcended ancient food production to the
laboratory synthesis of complex molecules. This evolution has been accelerated by …

Fe-catalyzed C–C bond construction from olefins via radicals

JC Lo, D Kim, CM Pan, JT Edwards… - Journal of the …, 2017 - ACS Publications
This Article details the development of the iron-catalyzed conversion of olefins to radicals
and their subsequent use in the construction of C–C bonds. Optimization of a reductive …

Scalable biocatalytic C–H oxyfunctionalization reactions

S Chakrabarty, Y Wang, JC Perkins… - Chemical Society …, 2020 - pubs.rsc.org
Catalytic C–H oxyfunctionalization reactions have garnered significant attention in recent
years with their ability to streamline synthetic routes toward complex molecules …

Decarboxylative alkenylation

JT Edwards, RR Merchant, KS McClymont, KW Knouse… - Nature, 2017 - nature.com
Olefin chemistry, through pericyclic reactions, polymerizations, oxidations, or reductions, has
an essential role in the manipulation of organic matter. Despite its importance, olefin …

Total Synthesis of abeo-Steroids via Cycloaddition Strategy

L Min, LP Zhong, CC Li - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Steroids continue to play a significant role in organic chemistry, medicinal
chemistry, and drug discovery due to their important biological activities and diverse …

Iron-and cobalt-catalyzed C (sp 3)–H bond functionalization reactions and their application in organic synthesis

Y Liu, T You, HX Wang, Z Tang, CY Zhou… - Chemical Society …, 2020 - pubs.rsc.org
Direct C–H bond functionalization catalyzed by non-precious transition metals is an
attractive strategy in synthetic chemistry. Compared with the precious metals rhodium …

Visible light-mediated NHCs and photoredox co-catalyzed radical 1, 2-dicarbonylation of alkenes for 1, 4-diketones

L Wang, J Sun, J Xia, M Li, L Zhang, R Ma… - Science China …, 2022 - Springer
Alkenes are ubiquitous, and the difunctionalization of alkenes represents one of the most
practical approaches for the construction of value-added compounds. Dicarbonylation of …