Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review

L Peivasteh-Roudsari, R Barzegar-Bafrouei, KA Sharifi… - Heliyon, 2023 - cell.com
Endocrine-disrupting chemicals (EDCs) are a growing public health concern worldwide.
Consumption of foodstuffs is currently thought to be one of the principal exposure routes to …

[PDF][PDF] Male reproductive toxicity of some selected metals: A review

N Mathur, G Pandey, GC Jain - Journal of biological sciences, 2010 - researchgate.net
The management of infertility problems has become an increasingly important part of health
services during the past 20 years. A substantial number of couples seek fertility treatment …

Designing endocrine disruption out of the next generation of chemicals

TT Schug, R Abagyan, B Blumberg, TJ Collins… - Green …, 2013 - pubs.rsc.org
A central goal of green chemistry is to avoid hazard in the design of new chemicals. This
objective is best achieved when information about a chemical's potential hazardous effects …

Tributyltin chloride induced testicular toxicity by JNK and p38 activation, redox imbalance and cell death in sertoli-germ cell co-culture

S Mitra, A Srivastava, S Khandelwal - Toxicology, 2013 - Elsevier
The widespread use of tributyltin (TBT) as biocides in antifouling paints and agricultural
chemicals has led to environmental and marine pollution. Human exposure occurs mainly …

Triorganotin compounds-ligands for “rexinoid” inducible transcription factors: biological effects

J Brtko, Z Dvorak - Toxicology Letters, 2015 - Elsevier
We review trialkyltin and triaryltin compounds, representing a class of organometallic
compounds that function as nuclear retinoid X receptors (RXR) agonists due to their …

The impact of endocrine-disrupting chemicals in male fertility: focus on the action of obesogens

L Rato, ACA Sousa - Journal of Xenobiotics, 2021 - mdpi.com
The current scenario of male infertility is not yet fully elucidated; however, there is increasing
evidence that it is associated with the widespread exposure to endocrine-disrupting …

A short-term exposure to tributyltin blocks leydig cell regeneration in the adult rat testis

X Wu, J Liu, Y Duan, S Gao, Y Lü, X Li, Q Zhu… - Frontiers in …, 2017 - frontiersin.org
Background: Tributyltin (TBT) is widely used as an antifouling agent that may cause
reproductive toxicity. The mechanism of TBT on Leydig cell development is still unknown …

Obesogens and male fertility

AM Cardoso, MG Alves, PP Mathur… - Obesity …, 2017 - Wiley Online Library
In the last decades, several studies evidenced a decrease in male fertility in developed
countries. Although the aetiology of this trend in male reproductive health remains a matter …

Steroid hormone related effects of marine persistent organic pollutants in human H295R adrenocortical carcinoma cells

MW van den Dungen, JCW Rijk, E Kampman… - Toxicology in Vitro, 2015 - Elsevier
Persistent organic pollutants (POPs) such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD),
polychlorobiphenyl (PCB) 126 and 153, perfluorooctanesulfonic acid (PFOS) …

Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans

Y Pu, S Pearl, J Gingrich, J Jing, D Martin… - Archives of …, 2019 - Springer
Tributyltin (TBT), an organotin chemical used as a catalyst and biocide, can stimulate
cholesterol efflux in non-steroidogenic cells. Since cholesterol is the first limiting step for sex …