Advances in synthesis of 2, 3-dihydroquinazolin-4 (1H)-ones
X Zhang, Y Zhu, Y Zhu, Z Li, G Zhang - Chinese Journal of Organic …, 2019 - sioc-journal.cn
Dihydroquinazolin-4 (1H)-one compounds are an important class of nitrogen-containing
fused heterocycles, which possess a wide range of pharmacological and biological activities …
fused heterocycles, which possess a wide range of pharmacological and biological activities …
A novel series of N-acyl substituted indole-linked benzimidazoles and naphthoimidazoles as potential anti inflammatory, anti biofilm and anti microbial agents
R Abraham, P Prakash, K Mahendran… - Microbial …, 2018 - Elsevier
A novel N-acyl substituted indole-linked benzimidazoles and naphthoimidazoles were
synthesized. Their chemical structures were confirmed using spectroscopic tools including 1 …
synthesized. Their chemical structures were confirmed using spectroscopic tools including 1 …
Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory …
Novel quinazolinones conjugated with indole acetamide (4a–c), ibuprofen (7a–e), or
thioacetohydrazide (13a, b, and 14a-d) were designed to increase COX-2 selectivity. The …
thioacetohydrazide (13a, b, and 14a-d) were designed to increase COX-2 selectivity. The …
Alkylamino‐Directed One‐Pot Reaction of N‐Alkyl Anilines with CO, Amines and Aldehydes Leading to 2,3‐Dihydroquinazolin‐4(1H)‐ones
X Zhang, Z Li, Q Ding, X Li, X Fan… - Advanced Synthesis & …, 2019 - Wiley Online Library
An economical and efficient approach to pharmaceutically and biologically significant 2, 3‐
dihydroquinazolin‐4 (1H)‐ones has been disclosed. The one‐pot multicomponent reaction …
dihydroquinazolin‐4 (1H)‐ones has been disclosed. The one‐pot multicomponent reaction …
Synthesis, in vivo and in silico evaluation of novel 2, 3‐dihydroquinazolin‐4 (1H)‐one derivatives as potential anticonvulsant agents
H Kothayer, SM Ibrahim, MK Soltan… - Drug Development …, 2019 - Wiley Online Library
In light of the pharmacophoric structural requirements for achieving anticonvulsant activity, a
series of N‐(1‐methyl‐4‐oxo‐2‐un/substituted‐1, 2‐dihydroquinazolin‐3 [4H]‐yl) …
series of N‐(1‐methyl‐4‐oxo‐2‐un/substituted‐1, 2‐dihydroquinazolin‐3 [4H]‐yl) …
Synthesis of 4-Aryl-1, 3, 4-benzotriazepinones from Isatoic Anhydrides and Hydrazonyl Chlorides
X Zhang, Y Pan, T Liu, Y Wang - The Journal of Organic …, 2023 - ACS Publications
An efficient synthesis of 4-aryl-1, 3, 4-benzotriazepinones from readily available isatoic
anhydrides and hydrazonyl chlorides was developed. In this facile protocol, a series of …
anhydrides and hydrazonyl chlorides was developed. In this facile protocol, a series of …
[PDF][PDF] A review on some synthetic methods of 4 (3H)-quinazolinone and benzotriazepine derivatives and their biological activities.
AS Abdelkhalek, ME Abokull, SM Ibrahim… - Organic …, 2024 - acgpubs.org
This concise review provides an overview of some synthetic methods utilized for the
preparation of 4 (3H)-quinazolinone and benzotriazepine derivatives, and explores their …
preparation of 4 (3H)-quinazolinone and benzotriazepine derivatives, and explores their …
Synthesis of aryl substituted 2, 4, 5, 6-tetrahydro-3H-1, 2, 4-triazepine-3-thiones/ones starting from chalcone-derived β-isothiocyanato ketones
AA Fesenko, MS Grigoriev, AD Shutalev - Tetrahedron, 2016 - Elsevier
A general two-step synthesis of 7-aryl substituted 2, 4, 5, 6-tetrahydro-3H-1, 2, 4-triazepine-3-
thiones from 1-aryl-3-isothiocyanatopropan-1-ones has been developed. The synthesis …
thiones from 1-aryl-3-isothiocyanatopropan-1-ones has been developed. The synthesis …
A convenient stereoselective access to novel 1, 2, 4-triazepan-3-ones/thiones via reduction or reductive alkylation of 7-membered cyclic semicarbazones and …
AA Fesenko, MS Grigoriev, AD Shutalev - Organic & Biomolecular …, 2018 - pubs.rsc.org
A general stereoselective approach to previously unknown 1, 2, 4-triazepane-3-
thiones/ones based on reduction or reductive alkylation of readily available 2, 4, 5, 6 …
thiones/ones based on reduction or reductive alkylation of readily available 2, 4, 5, 6 …