Eph receptors in cancer

S Arora, AM Scott, PW Janes - Biomedicines, 2023 - mdpi.com
Eph receptor tyrosine kinases play critical functions during development, in the formation of
tissue and organ borders, and the vascular and neural systems. Uniquely among tyrosine …

Unraveling the Significance of EPH/Ephrin Signaling in Liver Cancer: Insights into Tumor Progression and Therapeutic Implications

SP Papadakos, IE Stergiou, N Gkolemi, K Arvanitakis… - Cancers, 2023 - mdpi.com
Simple Summary This narrative literature review delves into the role of EPH/ephrin signaling
in liver cancer and its implications for tumor progression and potential therapeutic strategies …

The impact of histone modifications in endometriosis highlights new therapeutic opportunities

I Psilopatis, K Vrettou, FN Fleckenstein, S Theocharis - Cells, 2023 - mdpi.com
Endometriosis is a chronic disorder of the female reproductive system which afflicts a great
number of women worldwide. Histone deacetylases (HDACs) prevent the relaxation of …

Environmental explanation of prostate cancer progression based on the comprehensive analysis of polychlorinated biphenyls

WC Zheng, F Lin, YP Wu, ZB Ke, SH Chen… - Science of The Total …, 2024 - Elsevier
Abstract Objective Polychlorinated biphenyls (PCBs) have caused great environmental
concerns. The study aims to investigate underlying molecular mechanisms between PCBs …

Targeting Interleukin-13 Receptor α2 and EphA2 in Aggressive Breast Cancer Subtypes with Special References to Chimeric Antigen Receptor T-Cell Therapy

D Kashyap, H Salman - International Journal of Molecular Sciences, 2024 - mdpi.com
Breast cancer (BCA) remains the leading cause of cancer-related mortality among women
worldwide. This review delves into the therapeutic challenges of BCA, emphasizing the roles …

68 Ga labeled EphA2-targeted cyclic peptide: a novel positron imaging tracer for triple-negative breast cancer?

B Qu, X Li, Y Ma, Y Wang, Y Han, G Hou, F Gao - Dalton Transactions, 2024 - pubs.rsc.org
The absence of better biomarkers currently limits early diagnosis and treatment of triple-
negative breast cancer (TNBC). Our previously published study reported that the cyclic …

LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2

X Han, F Shi, S Guo, Y Li, H Wang, C Song… - World Journal of Surgical …, 2023 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are critical regulators in the
initiation and progression of breast cancer. Our study aims to characterize the functions of …

Over-Expression of EFNA2 in Lung Adenocarcinoma: EFNA2 Gene Expression Correlates with Shortened Survival

C Liu, Y Wu, H Zhou, X Ge… - Journal of …, 2024 - research.manuscritpub.com
Background: The incidence of lung adenocarcinoma (LUAD) is increasing worldwide with
different prognosis. Ephrin-A2 (EFNA2), a member of the Eph/ephrin family, is associated …

[PDF][PDF] Establishment of a highly sensitive and specific anti-EphB2 monoclonal antibody (Eb2Mab-12) for flow cytometry

R Ubukata, H Suzuki, M Hirose… - Microbes & …, 2025 - med-tohoku-antibody.com
Ephrin type-B receptor 2 (EphB2) is a member of the Eph family tyrosine kinase receptors.
EphB2 binds to ephrin-B1, ephrin-B2, and ephrin-B3, which are critical regulators of …

Mecanismo de acción de un aptámero frente a MNK1 en cáncer de mama

R Ferreras Martín - 2024 - docta.ucm.es
El cáncer de mama es el tipo de cáncer diagnosticado con mayor frecuencia con una
incidencia estimada de 2.3 millones de nuevos casos en el año 2020 y 685000 fallecidas …